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Advanced filters: Author: Daesong Yim Clear advanced filters

  • A number of advanced tumours appear to evade immune recognition by natural killer cells by shedding the soluble major histocompatibility complex class-I-related ligand MICA, which inactivates the NKG2D receptor. Now the mechanism of shedding is shown to involve the protein disulphide isomerase ERp5.

    • Brett K. Kaiser
    • Daesong Yim
    • Thomas Spies
    Research
    Nature
    Volume: 447, P: 482-486