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Showing 1–2 of 2 results
Advanced filters: Author: Dan-Pei Li Clear advanced filters

  • Inhibition of immunocyte infiltration and activation has been suggested to ameliorate hepatic inflammation and fibrosis in nonalcoholic steatohepatitis. Here, the authors show PirB/LILRB2 regulates the migration of macrophages during NASH by binding with ANGPTL8, which is involved in the regulation of NASH development.

    • Dan-Pei Li
    • Li Huang
    • Xue-Feng Yu
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Beige fat activation involves a fuel switch to fatty acid oxidation following chronic cold adaptation. Here, the authors show that Sortilin in adipose tissues facilitates the translocation of ACSL1 from the mitochondria to the endolysosomal pathway for degradation, which controls adipose tissue fatty acid oxidation and substrate fuel selection during beige fat activation.

    • Min Yang
    • Jing Ge
    • Yong Chen
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17