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Advanced filters: Author: Dania Zhivaki Clear advanced filters

  • Why are newborns more vulnerable to infection? Here, the authors explain that it is not the immaturity of the immune system per se, but the unique regulation of immune responses in early life that limits immunity to infection yet allows safe developmentin uteroand the accommodation of microbial colonization at birth.

    • Xiaoming Zhang
    • Dania Zhivaki
    • Richard Lo-Man
    Reviews
    Nature Reviews Immunology
    Volume: 17, P: 495-507

  • In this Perspective, the authors propose that innate immune detection of oxidized phospholipids, which result from tissue injury, allows the immune system to assess the degree of danger; the detection of oxidized phosphocholines in the presence of pathogen-associated molecular patterns or damage-associated molecular patterns triggers a heightened immune response.

    • Dania Zhivaki
    • Jonathan C. Kagan
    Reviews
    Nature Reviews Immunology
    Volume: 22, P: 322-330