The 23mer L5URcore peptide is identified, which binds with low micromolar affinity to Ras-binding domains, notably of Raf proteins, thus disrupting their galectin1-interaction, H-Ras-nanoclustering, -signalling and more broadly cell proliferation.
- Candy Laura Steffen
- Ganesh babu Manoharan
- Daniel Kwaku Abankwa