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Showing 1–2 of 2 results
Advanced filters: Author: Daniel Aguilar-Hidalgo Clear advanced filters

  • Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances the diffusion of the cell signalling protein Wingless.

    • Emile G. Magny
    • Ana Isabel Platero
    • Juan Pablo Couso
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • A mechanism involving intracellular recycling of the morphogen Decapentaplegic (Dpp) underlies the scaling of the Dpp gradient in the Drosophila wing disc, and this is modulated by the extracellular factors Pentagone and Dally.

    • Maria Romanova-Michaelides
    • Zena Hadjivasiliou
    • Marcos Gonzalez-Gaitan
    Research
    Nature
    Volume: 602, P: 287-293