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Showing 1–2 of 2 results
Advanced filters: Author: Daniel Taibo Clear advanced filters

  • Acetaminophen-induced liver injury is one of the most common causes of liver failure and has to be treated within hours of the overdose. Here Barbier-Torres et al. show that targeting MCJ, a mitochondrial negative regulator, even 24 h after the overdose protects liver from acetaminophen-induced damage.

    • Lucía Barbier-Torres
    • Paula Iruzubieta
    • María Luz Martínez-Chantar
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11

  • This study presents in vitro, in vivo, and human genetic evidence showing that the chromatin regulator SmarcAL1 plays an indispensable role in regulating cellular lipid metabolism, a mechanism linked to the lipid phenotypes seen in SIOD patients.

    • Taylor Hanta Nagai
    • Chrissy Hartigan
    • Yu-Xin Xu
    ResearchOpen Access
    Communications Biology
    Volume: 6, P: 1-13