Synaptic adhesion molecules are known to regulate synapse development, but growing evidence indicates that they also regulate synaptic function and plasticity. The authors report a novel synaptic adhesion molecule, IgSF11, that regulates excitatory synaptic transmission and plasticity through its dual interaction with the postsynaptic scaffold PSD-95 and AMPA receptors.
- Seil Jang
- Daeyoung Oh
- Eunjoon Kim
