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Showing 1–2 of 2 results
Advanced filters: Author: Dannele Echemendia-Blanco Clear advanced filters

  • The replication of the two chromosomes in the bacterium Vibrio cholerae is coordinated through the binding of initiator protein RctB to a checkpoint sequence, crtS. Here, Niault et al. study RctB binding dynamics across the V. cholerae cell cycle to shed light into the underlying mechanisms.

    • Théophile Niault
    • Ariel Talavera
    • Marie-Eve Val
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Toxic small alarmone synthetase (toxSAS) enzymes are toxic effectors of certain toxin–antitoxin modules, involved in phage defense and secretion systems. Here the authors establish the mechanism underlying toxSAS inhibition by structured antitoxins and reveal the connection between neutralization strategy and substrate specificity.

    • Lucia Dominguez-Molina
    • Tatsuaki Kurata
    • Abel Garcia-Pino
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 21, P: 182-192