Type 1 diabetes (T1D) was described as an autoimmune disease more than 25 years ago, but the mechanisms involved in this disease are not yet completely understood. Here, the authors review the current models of how T1D disease develops and discuss the steps that will need to be taken to develop more successful therapies for patients.
- Kevan C. Herold
- Dario A. A. Vignali
- Jeffrey A. Bluestone
