Although effective treatments for rheumatoid arthritis are now available, many patients are found to be unresponsive to, or cannot tolerate, particular therapeutic options; therefore, selecting the most appropriate treatment on an individualized basis is important. Genetic and epigenetic factors probably represent key determinants of a patient's response to therapy, and herein the potential of such factors as predictive biomarkers of therapeutic responsiveness is discussed.
- Darren Plant
- Anthony G. Wilson
- Anne Barton
