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Showing 1–11 of 11 results
Advanced filters: Author: Darrin Pochan Clear advanced filters

  • Electrically conductive hydrogels based on conducting polymers often rely on covalent and therefore irreversible crosslinking mechanisms. Here, the authors report a thermo-responsive conducting polymer that undergoes a fully reversible non-covalent crosslinking at 35 °C within less than a minute to form conductive hydrogels.

    • Vidhika S. Damani
    • Xinran Xie
    • Laure V. Kayser
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Cation binding is shown to trigger mesoscale domain formation within assembled mixtures of neutral and anionic polymer amphiphiles. The spotted and striped particles could be used for drug delivery or biomedical sensing.

    • Darrin J. Pochan
    News & Views
    Nature Materials
    Volume: 8, P: 773-774

  • Surface charge patchiness has a great impact on the aggregation and solution stability of colloidal particles and globular proteins. Here, the authors report the solution behaviours of computationally designed peptide coiled-coil ‘bundlemer’ nanoparticles with controlled surface charge patchiness where only a single type of surface charge is allowed.

    • Yi Shi
    • Tianren Zhang
    • Darrin J. Pochan
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11

  • Compositionally and geometrically complex nano-objects are an important goal in medicinal, photonic and electronic materials research. Here, the authors fabricate disk-sphere and disk-cylinder nanoparticles with defined multicompartments from binary mixtures of block copolymers.

    • Jiahua Zhu
    • Shiyi Zhang
    • Darrin J. Pochan
    Research
    Nature Communications
    Volume: 4, P: 1-7

  • mRNA delivery through LNPs targeting specific organs holds great clinical potential, but it remains unclear how the structure of the lipidoids in the LNPs controls organ tropism. Here the authors direct in vivo delivery of siloxane-based LNPs via structural alteration of the ionizable structure of the constituting lipidoids.

    • Lulu Xue
    • Gan Zhao
    • Michael J. Mitchell
    Research
    Nature Nanotechnology
    Volume: 20, P: 132-143

  • In block copolymer vesicles, crystallization often leads to defects and renders the structures leaky that undermines their potential biomedical application. Here the authors use an emulsion solution method to control the crystallization of an amphiphilic block copolymer at the curved liquid/liquid interface to improve the blood circulation time.

    • Hao Qi
    • Hao Zhou
    • Christopher Y. Li
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10

  • Gels formed by metal–ligand coordination typically consist of single metal ions linked together by polymer chains. Now, metal–organic cages have been used as junctions instead. A gel was prepared that features a large number of polymer chains at each junction, including loops that further serve to functionalize the material.

    • Aleksandr V. Zhukhovitskiy
    • Mingjiang Zhong
    • Jeremiah A. Johnson
    Research
    Nature Chemistry
    Volume: 8, P: 33-41