Nature Search

The hot interstellar medium toward SN1987A

Qingde Wang
Thomas Hamilton
David J. Helfand
Research28 Sept 1989
Nature

Volume: 341, P: 309-311
Detecting structural heart disease from electrocardiograms using AI

EchoNext, a deep learning model for electrocardiograms trained and validated in diverse health systems, successfully detects many forms of structural heart disease, supporting the potential of artificial intelligence to expand access to heart disease screening at scale.

Timothy J. Poterucha
Linyuan Jing
Pierre Elias
ResearchOpen Access16 Jul 2025
Nature

Volume: 644, P: 221-230
15 years of Nature Physics

Over the last 15 years, the content of Nature Physics has covered an enormous breadth of subjects at the forefront of physics. The journal’s past and present editors recount their favourite papers and what made chaperoning them to publication special.

Alison Wright
Ed Gerstner
Elizaveta Dubrovina
Special Features01 Oct 2020
Nature Physics

Volume: 16, P: 999-1005
Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination

Intravital imaging reveals macrophage-driven de novo induction of cancer stem cells in vivo, and their dramatic enrichment on dissemination through TMEM doorways. These findings provide a mechanism for the validated ability of TMEM doorway density to be prognostic for distant recurrence of metastatic tumors in breast cancer patients.

Ved P. Sharma
Binwu Tang
Maja H. Oktay
ResearchOpen Access15 Dec 2021
Nature Communications

Volume: 12, P: 1-24
Neutron scattering and thermodynamic evidence for emergent photons and fractionalization in a pyrochlore spin ice

Quantum spin-ice phases are predicted to have emergent gauge fields and fractionalization. Neutron scattering and thermodynamic measurements of the quantum spin-ice candidate Ce₂Zr₂O₇ show features consistent with these predictions.

Bin Gao
Félix Desrochers
Pengcheng Dai
Research19 Jun 2025
Nature Physics

Volume: 21, P: 1203-1210
GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes

Antine E. Stenbit
Tsu-Shuen Tsao
Maureen J. Charron
Research01 Oct 1997
Nature Medicine

Volume: 3, P: 1096-1101
Probabilistic photonic computing with chaotic light

A photonic computing platform using chaotic light for probabilistic arithmetic enables ultrafast, parallel processing. The system predicts classification and uncertainty simultaneously. The optical architecture allows efficient distribution evaluations at each output in a single time step.

Frank Brückerhoff-Plückelmann
Hendrik Borras
Wolfram Pernice
ResearchOpen Access01 Dec 2024
Nature Communications

Volume: 15, P: 1-10
A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies

MultiSTAAR provides a general and flexible statistical framework for functionally informed multi-trait rare variant analysis of biobank-scale sequencing studies by jointly analyzing multiple traits and incorporating annotation information.

Xihao Li
Han Chen
Xihong Lin
Research07 Feb 2025
Nature Computational Science

Volume: 5, P: 125-143
Absorption imaging of a single atom

Absorption imaging relies on the capture of photons by an object to create intensity contrasts, allowing for the visualization of small quantum systems. Streedet al. demonstrate the first absorption imaging of an isolated ytterbium ion, with contrast at the limit of semiclassical theory.

Erik W. Streed
Andreas Jechow
David Kielpinski
Research03 Jul 2012
Nature Communications

Volume: 3, P: 1-5
Estimation of reference curves for brain atrophy and analysis of robustness to machine effects

Elodie Piot
Félix Renard
Maria Luisa Mandelli
ResearchOpen Access03 Oct 2025
Scientific Reports

Volume: 15, P: 1-21
Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancer

The epigenetic mechanisms underlying phenotypic diversity across different metastatic sites in castration-resistant prostate cancer (CRPC) remain to be characterised. Here, multi-omic profiling across metastatic lesions identifies regulatory networks driving tumour lineage programs and potential therapeutic targets.

Kei Mizuno
Sheng-Yu Ku
Himisha Beltran
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Demise of the Lemaître cosmological models and objects at large redshift

David Tytler
Research28 May 1981
Nature

Volume: 291, P: 289-292
Soft X-ray prompt emission from the high-redshift gamma-ray burst EP240315a

The death of massive stars has traditionally been discovered by explosive events in the gamma-ray band. Liu et al. show that the sensitive wide-field monitor on board Einstein Probe can reveal a weak soft-X-ray signal much earlier than gamma rays.

Y. Liu
H. Sun
X.-X. Zuo
Research23 Jan 2025
Nature Astronomy

Volume: 9, P: 564-576
A direct test of E=mc²

Simon Rainville
James K. Thompson
David E. Pritchard
Research21 Dec 2005
Nature

Volume: 438, P: 1096-1097
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk

Analyses of genome and exome sequencing data identify rare coding and structural variants associated with atrial fibrillation and highlight genetic links between atrial fibrillation and cardiomyopathies.

Seung Hoan Choi
Sean J. Jurgens
Patrick T. Ellinor
Research06 Mar 2025
Nature Genetics

Volume: 57, P: 548-562
Polaron spin dynamics in high-mobility polymeric semiconductors

The long spin lifetimes observed in polymeric semiconductors hold promise for potential applications. A careful study untangles the main mechanism behind them.

Sam Schott
Uday Chopra
Henning Sirringhaus
Research03 Jun 2019
Nature Physics

Volume: 15, P: 814-822
Evidence for role of m⁷G^5′-phosphate group in recognition of eukaryotic mRNA by initiation factor IF-M₃

David A. Shafritz
Joel A. Weinstein
Corrado Baglioni
Research01 May 1976
Nature

Volume: 261, P: 291-294
Molecular Hydrogen in Pre-galactic Gas Clouds

WILLIAM C. SASLAW
DAVID ZIPOY
Research01 Dec 1967
Nature

Volume: 216, P: 976-978
Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes

Cells can regulate their mass density. Here, the authors demonstrate how eukaryotes establish and maintain a lower density in the nucleus than in the cytoplasm via pressure balance, and how deviations emerge during pathophysiological states like senescence.

Abin Biswas
Omar Muñoz
Simone Reber
ResearchOpen Access15 Aug 2025
Nature Communications

Volume: 16, P: 1-18
Genetic heterogeneity of Barter's syndrome revealed by mutations in the K⁺ channel, ROMK

David B. Simon
Fiona E. Karet
Richard P. Lifton
Research01 Oct 1996
Nature Genetics

Volume: 14, P: 152-156
Quantum gas mixtures and dual-species atom interferometry in space

Using upgraded hardware of the multiuser Cold Atom Lab (CAL) aboard the International Space Station (ISS), Bose–Einstein condensates (BECs) of two atomic isotopes are simultaneously created and used to demonstrate interspecies interactions and dual species atom interferometry in space.

Ethan R. Elliott
David C. Aveline
Jason R. Williams
Research15 Nov 2023
Nature

Volume: 623, P: 502-508
Room-temperature cavity exciton-polariton condensation in perovskite quantum dots

Colloidal perovskite quantum dots hold promise for polaritonic devices with strong excitonic confinement. Here the authors report the observation of room-temperature cavity exciton-polariton condensation in a perovskite-based quantum dot solid, opening the door towards quantum and photonics applications.

Ioannis Georgakilas
David Tiede
Thilo Stöferle
ResearchOpen Access05 Jun 2025
Nature Communications

Volume: 16, P: 1-8
Giant superfluorescent bursts from a semiconductor magneto-plasma

Superfluorescence—the emission of coherent light from an initially incoherent collection of excited dipoles—is now identified in a semiconductor. Laser-excited electron–hole pairs spontaneously polarize and then abruptly decay to produce intense pulses of light.

G. Timothy Noe II
Ji-Hee Kim
Junichiro Kono
Research29 Jan 2012
Nature Physics

Volume: 8, P: 219-224
Single-molecule imaging of transcription dynamics in somatic stem cells

Single-molecule fluorescence in situ hybridization and live-cell imaging are used to study the contribution of transcriptional noise to stem cell heterogeneity, revealing that stochastic transcription dynamics are conducive to concomitant stem-cell maintenance and tissue homeostasis.

Justin C. Wheat
Yehonatan Sella
Ulrich Steidl
Research24 Jun 2020
Nature

Volume: 583, P: 431-436
Spin Up in Neutron Stars : The Future of the Vela Pulsar

GORDON BAYM
CHRISTOPHER PETHICK
MALVIN RUDERMAN
Research29 Nov 1969
Nature

Volume: 224, P: 872-874
How to be an astronomer

David Hughes
Books & Arts23 Mar 1995
Nature

Volume: 374, P: 318-319
An active current sheet in the solar wind

Steven J. Schwartz
Chris P. Chaloner
Les J. C. Woolliscroft
Research21 Nov 1985
Nature

Volume: 318, P: 269-271
Broadband optical phonon scattering reduces the thermal conductivity of multi-cation oxides

The authors observe a reduction in thermal conductivity when transitioning from single to multi-cation oxides, exploring the role of local bonding distortions in phonon scattering and thermal transport.

William T. Riffe
Saman Zare
Patrick E. Hopkins
ResearchOpen Access08 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Why is the Universe open?

David Lindley
Research04 Jun 1981
Nature

Volume: 291, P: 391-392
Cell cycle duration determines oncogenic transformation capacity

Total cell cycle duration is a key hallmark of cancer initiation, and determines whether defects in apoptosis, senescence, immune surveillance, angiogenesis, DNA repair, polarity and proliferation lead to cancer development.

Danian Chen
Suying Lu
Rod Bremner
ResearchOpen Access30 Apr 2025
Nature

Volume: 641, P: 1309-1318
Crystal structure at 2.8 Å resolution of a soluble form of the cell adhesion molecule CD2

E. Yvonne Jones
Simon J. Davis
David I. Stuart
Research19 Nov 1992
Nature

Volume: 360, P: 232-239
Electrically tunable organic–inorganic hybrid polaritons with monolayer WS₂

Hybrid polariton states originating from the strong coupling of photonic and excitonic states hold promise for control of nonlinear light behaviour. Here, the authors fabricate a microcavity containing organic dye and WS₂, featuring hybrid polaritons arising from both Frenkel and Wannier-Mott excitons.

Lucas C. Flatten
David M. Coles
Jason M. Smith
ResearchOpen Access17 Jan 2017
Nature Communications

Volume: 8, P: 1-5
Identification of integrated hepatitis B virus DNA and expression of viral RNA in an HBsAg-producing human hepatocellular carcinoma cell line

Prasanta R. Chakraborty
Nelson Ruiz-Opazo
David A. Shafritz
Research31 Jul 1980
Nature

Volume: 286, P: 531-533
Palaearctic Grasshoppers

DAVID R. RAGGE
Books & Arts14 Aug 1965
Nature

Volume: 207, P: 673-674
Expression of human immune interferon cDNA in E. coli and monkey cells

Patrick W. Gray
David W. Leung
David V. Goeddel
Research11 Feb 1982
Nature

Volume: 295, P: 503-508
Capturing the light

David H. DeVorkin
Books & Arts23 Mar 1995
Nature

Volume: 374, P: 317-318
H1 histones control the epigenetic landscape by local chromatin compaction

Experiments using a conditional triple-knockout mouse strain show that histone H1 regulates the activity of chromatin domains by controlling chromatin compaction, genome architecture and histone methylation.

Michael A. Willcockson
Sean E. Healton
Arthur I. Skoultchi
Research09 Dec 2020
Nature

Volume: 589, P: 293-298
Advancing simulations of coupled electron and phonon nonequilibrium dynamics using adaptive and multirate time integration

Jia Yao
Ivan Maliyov
Marco Bernardi
ResearchOpen Access07 Aug 2025
npj Computational Materials

Volume: 11, P: 1-11
Protein-folding dynamics

Martin Karplus
David L. Weaver
Research01 Apr 1976
Nature

Volume: 260, P: 404-406
Observation of two-dimensional Anderson localisation of ultracold atoms

Anderson localization has been previously reported in 1D and 3D but it has remained elusive in 2D environments. Here the authors report probable observation of 2D Anderson localization using ultracold atoms in a weak interaction regime.

Donald H. White
Thomas A. Haase
David A. W. Hutchinson
ResearchOpen Access02 Oct 2020
Nature Communications

Volume: 11, P: 1-8
Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion

A compound screen using zebrafish identified carbonic anhydrase (CA) as a modulator of tau toxicity. CA inhibition abrogates lysosomal acidification and causes tau secretion by lysosomal exocytosis without having a prion effect. This mechanism lowers intracellular tau and is neuroprotective in zebrafish and mouse models of tauopathy.

Ana Lopez
Farah H. Siddiqi
David C. Rubinsztein
ResearchOpen Access31 Oct 2024
Nature Chemical Biology

Volume: 21, P: 577-587
Network Cosmology

Dmitri Krioukov
Maksim Kitsak
Marián Boguñá
ResearchOpen Access16 Nov 2012
Scientific Reports

Volume: 2, P: 1-6
Optical analogues of the Newton–Schrödinger equation and boson star evolution

In the weak field limit, boson star evolution is governed by the Newton-Schrödinger equation. Here the authors report an optical setup that provides a formal analogue of such dynamics via the interaction between vortex beams and a medium with positive thermo-optical nonlinearity.

Thomas Roger
Calum Maitland
Daniele Faccio
ResearchOpen Access14 Nov 2016
Nature Communications

Volume: 7, P: 1-8
Limits on variation of G from clusters of galaxies

DAVID S. DEARBORN
DAVID N. SCHRAMM
Research15 Feb 1974
Nature

Volume: 247, P: 441-443
Observation of stellar remnants from recent Supernovae

David J. Helfand
Robert H. Becker
Reviews19 Jan 1984
Nature

Volume: 307, P: 215-221
Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells

The understanding of the mechanisms underlying the ability of disseminated tumor cells (DTCs) to form metastasis is incomplete. Here, by using high-resolution intravital imaging of the murine lung to track the fate of breast-derived DTCs, the authors show that macrophages within the primary tumor induce a pro-dissemination and pro-dormancy phenotype in tumor cells, favouring their extravasation in the lung.

Lucia Borriello
Anouchka Coste
David Entenberg
ResearchOpen Access02 Feb 2022
Nature Communications

Volume: 13, P: 1-19
Extragalactic nature of G227.1 + 1.0

Gary A. Chanan
David J. Helfand
Kate Ebneter
Research06 Mar 1986
Nature

Volume: 320, P: 41-42
Solar system expansion and strong equivalence principle as seen by the NASA MESSENGER mission

The NASA MESSENGER mission collected a rich dataset enabling determination of Mercury’s ephemeris. Here, the authors analyse MESSENGER data obtained over an extended period of time to quantify parameters related to General Relativity.

Antonio Genova
Erwan Mazarico
Maria T. Zuber
ResearchOpen Access18 Jan 2018
Nature Communications

Volume: 9, P: 1-9
Plasma diagnostics in an astrophysical setting

David J. Helfand
News & Views01 Oct 1981
Nature

Volume: 293, P: 338-339
A luminous and young galaxy at z = 12.33 revealed by a JWST/MIRI detection of Hα and [O iii]

The detection of Hα reported in galaxy candidate GHZ2/GLASS-z12 provides a direct probe of star formation activity and can be used to trace massive stars with ages of ~10 Myr or younger.

Jorge A. Zavala
Marco Castellano
L. Y. Aaron Yung
ResearchOpen Access30 Oct 2024
Nature Astronomy

Volume: 9, P: 155-164

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