Nature Search

Polygenic and developmental profiles of autism differ by age at diagnosis

A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.

Xinhe Zhang
Jakob Grove
Varun Warrier
ResearchOpen Access01 Oct 2025
Nature

P: 1-12
Rewiring of cortical glucose metabolism fuels human brain cancer growth

The cortex fuels essential physiological processes with glucose-derived carbon, while gliomas fuel their aggressiveness by rerouting glucose carbon pathways and scavenging alternative carbon sources such as environmental amino acids, providing a potential therapeutic target.

Andrew J. Scott
Anjali Mittal
Daniel R. Wahl
ResearchOpen Access03 Sept 2025
Nature

Volume: 646, P: 413-422
Using co-sharing to identify use of mainstream news for promoting potentially misleading narratives

Goel et al. examine why some factually correct news articles are often shared by users who also shared fake news articles on social media.

Pranav Goel
Jon Green
Philip S. Resnik
Research10 Jun 2025
Nature Human Behaviour

Volume: 9, P: 1843-1860
FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult central nervous system

The homeostasis of myelin in the central nervous system is highly regulated, but the underlying mechanisms are unclear. Here, the authors show that the FBXW7 protein has a role in constraining myelin growth in the developing and adult central nervous system, preventing the accumulation of myelin abnormalities. FBXW7 acts in part through targeting the MYRF transcription factor for degradation.

Hannah Y. Collins
Ryan A. Doan
Ben Emery
ResearchOpen Access21 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Jellyfish as vectors of bacterial disease for farmed fish.

Hugh Ferguson
Christian Delannoy
Steven Hay
ResearchOpen Access17 Aug 2009
Nature Precedings

P: 1
Direct in situ observations of eruption-associated magnetic reconnection in the solar corona

Magnetic reconnection, thought to drive solar eruptions, has been studied with remote sensing. The Parker Solar Probe has directly measured reconnection-associated plasma properties in situ in the solar corona, deepening our understanding of the process.

Ritesh Patel
Tatiana Niembro
Gherardo Valori
Research13 Aug 2025
Nature Astronomy

P: 1-11
Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q

Michael R. Stratton
Deborah Ford
David E. Goldgar
Research01 May 1994
Nature Genetics

Volume: 7, P: 103-107
The Conflict Between Evolutionary Theory and Christian Belief

DAVID LACK
Research09 Jul 1960
Nature

Volume: 187, P: 98-100
Ben Nevis Observatory

DAVID MILNE HOME
Research01 Mar 1883
Nature

Volume: 27, P: 411
Absence of Organic Phase in Echinoderm Calcite

J. D. CURREY
DAVID NICHOLS
Research01 Apr 1967
Nature

Volume: 214, P: 81-83
Induction of dopaminergic neuron phenotype in the midbrain by Sonic hedgehog protein

Monica Z. Wang
Ping Jin
Kevin Pang
Research01 Nov 1995
Nature Medicine

Volume: 1, P: 1184-1188
Global evolution of inflammatory bowel disease across epidemiologic stages

An analysis of data from 522 population-based studies encompassing 82 global regions and spanning more than a century (1920–2024) shows spatiotemporal transitions across epidemiologic stages 1 to 3 of inflammatory bowel disease, and models stage 4 progression.

Lindsay Hracs
Joseph W. Windsor
Gilaad G. Kaplan
ResearchOpen Access30 Apr 2025
Nature

Volume: 642, P: 458-466
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Expanding and exploring the diversity of phytoplasmas from lucerne (Medicago sativa)

David Gopurenko
Murray J. Fletcher
Geoff M. Gurr
ResearchOpen Access25 Nov 2016
Scientific Reports

Volume: 6, P: 1-7
Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses

Study shows PTSD predisposition shares distinct genes and genomic regions with several cardiovascular conditions. Here the findings reveal neuronal, immune, and metabolic pathways, and repurposed drug targets that further the understanding of the comorbidity.

Jie Shen
Wander Valentim
Gita A. Pathak
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-17
The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule

Stephen B. Mcmahon
David L.H. Bennett
David L. Shelton
Research01 Aug 1995
Nature Medicine

Volume: 1, P: 774-780
Genetic variation in wild populations of rain-forest trees

YIK-YUEN GAN
FORBES W. ROBERTSON
DAVID W. LEE
Research01 Sept 1977
Nature

Volume: 269, P: 323-325
On Volcanoes

DAVID FORBES
Research25 Aug 1870
Nature

Volume: 2, P: 336-337
Complement-fixing Antibody to Colloid and Epithelium in Monkey Thyroiditis

DAVID KOFFLER
FIORENZO PARONETTO
Research14 Aug 1965
Nature

Volume: 207, P: 773-774
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial

Results from the phase 2 MATCH01 clinical trial of autologous monocyte-derived macrophage therapy for liver cirrhosis revealed no liver-related severe adverse events or deaths in the treatment group.

Paul N. Brennan
Mark MacMillan
Stuart J. Forbes
ResearchOpen Access10 Jan 2025
Nature Medicine

Volume: 31, P: 979-987
Mallet-Palmieri's “Vesuvius”

DAVID FORBES
Research04 Sept 1873
Nature

Volume: 8, P: 362-363
Mr. R. E. Richardson

DAVID H. THOMPSON
Comments & Opinion08 Jun 1935
Nature

Volume: 135, P: 946-947
The HIV A (sor) gene product is essential for virus infectivity

Klaus Strebel
Daryl Daugherty
Malcolm A. Martin
Research20 Aug 1987
Nature

Volume: 328, P: 728-730
Pineal and Adrenal Effects on Calcium Homeostasis in the Rat

David O Hakanson
William H Bergstrom
Research01 Jun 1990
Pediatric Research

Volume: 27, P: 571-573
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

Multi-ancestry genome-wide analyses identify 95 loci associated with post-traumatic stress disorder and implicate candidate genes, pathways and neurobiological systems underlying its pathophysiology.

Caroline M. Nievergelt
Adam X. Maihofer
Karestan C. Koenen
Research18 Apr 2024
Nature Genetics

Volume: 56, P: 792-808
Hotspot-spin axis motion or magnetic far-sided effect?

David Epp
William W. Sager
Stephen R. Hammond
Research26 May 1983
Nature

Volume: 303, P: 318-320
Novel genetic loci associated with hippocampal volume

The hippocampus in mammalian brain varies in size across individuals. Here, Hibar and colleagues perform a genome-wide association meta-analysis to find six genetic loci with significant association to hippocampus volume.

Derrek P. Hibar
Hieab H. H. Adams
M. Arfan Ikram
ResearchOpen Access18 Jan 2017
Nature Communications

Volume: 8, P: 1-12
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Paul R Burton
David G Clayton
Matthew A Brown
Research21 Oct 2007
Nature Genetics

Volume: 39, P: 1329-1337
The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP96 and class I homeoprotein HOXA9

Julian Borrow
Amanda M. Shearman
David E. Housman
Research01 Feb 1996
Nature Genetics

Volume: 12, P: 159-167
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Fine-mapping of causal variants and integration of epigenetic and chromatin conformation data identify likely target genes for 150 breast cancer risk regions.

Laura Fachal
Hugues Aschard
Alison M. Dunning
Research07 Jan 2020
Nature Genetics

Volume: 52, P: 56-73
Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16
Measuring exposure to misinformation from political elites on Twitter

Misinformation online can be shared by major political figures and organizations. Here, the authors developed a method to measure exposure to information from these sources on Twitter, and show how exposure relates to the quality of the content people share and their political ideology.

Mohsen Mosleh
David G. Rand
ResearchOpen Access21 Nov 2022
Nature Communications

Volume: 13, P: 1-9
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

Michael I. Bukrinsky
Sheryl Haggerty
Mario Stevenson
Research01 Oct 1993
Nature

Volume: 365, P: 666-669
Soft-bodied fossils from a Silurian volcaniclastic deposit

Derek E. G. Briggs
David J. Siveter
Derek J. Siveter
Research18 Jul 1996
Nature

Volume: 382, P: 248-250
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing

Microtubule-destabilizing drugs and oncolytic viruses are two unrelated approaches to battle cancer. Here the authors show that microtubule-destabilizing drugs potentiate the efficiency of oncolytic rhabdoviruses by altering the cytokine production and response of the tumour cells.

Rozanne Arulanandam
Cory Batenchuk
Jean-Simon Diallo
Research30 Mar 2015
Nature Communications

Volume: 6, P: 1-14
Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy

Immunoglobulin E (IgE)-mediated food allergy is a major issue that affects 2–10% of infants. Here the authors study the epigenetic regulation of the naive CD4+ T cell activation response among children with IgE-mediated food allergy finding epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex.

David Martino
Melanie Neeland
Richard Saffery
ResearchOpen Access17 Aug 2018
Nature Communications

Volume: 9, P: 1-12
Attack Behaviour in Mice inhibited by Δ-9-Tetrahydrocannabinol

M. MARLYNE KILBEY
G. EDWARD FRITCHIE
KENNETH M. JOHNSON
Research25 Aug 1972
Nature

Volume: 238, P: 463-465
Occipital horn syndrome and a mild Menkes phenotype associated with splice site mutations at the MNK locus

Stephen G. Kaler
Linda K. Gallo
William A. Gahl
Research01 Oct 1994
Nature Genetics

Volume: 8, P: 195-202
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

Mirchandani and colleagues show that tissue hypoxia alters the number and phenotype of circulating monocytes and their differentiation into lung macrophages, with important implications for the resolution of inflammation in the lung.

Ananda S. Mirchandani
Stephen J. Jenkins
Sarah R. Walmsley
ResearchOpen Access27 May 2022
Nature Immunology

Volume: 23, P: 927-939
Hepatic progenitor cells of biliary origin with liver repopulation capacity

Forbes and colleagues report on a population of hepatic progenitor cells that regenerate the adult liver in a mouse model where more than 98% of all hepatocytes are irreversibly damaged.

Wei-Yu Lu
Thomas G. Bird
Stuart J. Forbes
Research20 Jul 2015
Nature Cell Biology

Volume: 17, P: 971-983
Collective cell guidance by cooperative intercellular forces

The mechanical stresses within and between cells inside an advancing cellular monolayer are mapped experimentally. Cellular migration is found to be oriented in the direction of maximum principal stress indicating that cells collectively migrate to maintain minimal local intercellular shear stress.

Dhananjay T. Tambe
C. Corey Hardin
Xavier Trepat
Research22 May 2011
Nature Materials

Volume: 10, P: 469-475
Tracking the ultraviolet-induced photochemistry of thiophenone during and after ultrafast ring opening

Photoinduced isomerization reactions, including ring-opening reactions, lie at the heart of many chemical processes in nature. The pathway and dynamics of the ring opening of a model heterocycle have now been investigated by femtosecond photoelectron spectroscopy combined with ab initio theory, enabling the visualization of rich dynamics in both the ground and excited electronic states.

Shashank Pathak
Lea M. Ibele
Daniel Rolles
Research20 Jul 2020
Nature Chemistry

Volume: 12, P: 795-800
Reconstitution of SPO11-dependent double-strand break formation

Reconstitution of recombinantly expressed SPO11–TOP6BL complex recapitulates its DNA cleavage function and together with structural modelling and biochemical experiments, provides insights into the regulation and mechanism of SPO11 activity.

Zhi Zheng
Lyuqin Zheng
Scott Keeney
ResearchOpen Access19 Feb 2025
Nature

Volume: 639, P: 784-791
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Post-traumatic stress disorder (PTSD) is a common mental health problem. Here, the authors report a GWAS from the Psychiatric Genomics Consortium in which they identify two risk loci in European ancestry and one locus in African ancestry individuals and find that PTSD is genetically correlated with several other psychiatric traits.

Caroline M. Nievergelt
Adam X. Maihofer
Karestan C. Koenen
ResearchOpen Access08 Oct 2019
Nature Communications

Volume: 10, P: 1-16
Factors associated with COVID-19-related death using OpenSAFELY

OpenSAFELY, a new health analytics platform that includes data from over 17 million adult NHS patients in England, is used to examine factors associated with COVID-19-related death.

Elizabeth J. Williamson
Alex J. Walker
Ben Goldacre
Research08 Jul 2020
Nature

Volume: 584, P: 430-436
Newspaper Science

DAVID FORBES
Research12 Oct 1871
Nature

Volume: 4, P: 464
Impacts of climate change and extreme weather on food supply chains cascade across sectors and regions in Australia

The complex nature of food supply chains makes it a crucial exercise to estimate the impacts of disruptions caused by climate disasters. By applying an integrated modelling framework to Australia and considering heatwaves, cyclones and other climate events, this study presents novel ways of quantifying regional and sectoral spillover effects—including job and income losses, food and nutrient availability, and diet quality.

Arunima Malik
Mengyu Li
Mikhail Prokopenko
Research18 Aug 2022
Nature Food

Volume: 3, P: 631-643
Outcrossing rate and self-incompatibility in the colonizing species Senecio squalidus

Richard J Abbott
David G Forbes
Research01 Aug 1993
Heredity

Volume: 71, P: 155-159
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

An exciting genome-wide association study in the British population for seven common diseases. This analysis confirms previously identified loci and provides strong evidence for many novel disease susceptibility loci.

Paul R. Burton
David G. Clayton
Jane Worthington
Research07 Jun 2007
Nature

Volume: 447, P: 661-678
Impact of dietary carbohydrate type and protein–carbohydrate interaction on metabolic health

Simpson and colleagues systematically interrogate the influence of dietary carbohydrate type and quality on the obesogenic impact of protein-diluted diets in mice.

Jibran A. Wali
Annabelle J. Milner
Stephen J. Simpson
Research08 Jun 2021
Nature Metabolism

Volume: 3, P: 810-828

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