Using crosses between two strains of mice, one of which is susceptible and the other resistant to tumour development, these authors mapped genetic variants that contribute to skin cancer susceptibility. By combining these data with gene expression in normal skin they generated a network view of the gene expression architecture of mouse skin and identify expression motifs that contribute to tissue organization and various biological functions.
- David A. Quigley
- Minh D. To
- Allan Balmain
