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Showing 1–50 of 149 results

Advanced filters: Author: David G. McLeod Clear advanced filters

Microsurgical management of neovascularisation secondary to posterior segment ischaemia

David McLeod
Research01 Mar 1991
Eye

Volume: 5, P: 252-259
Long-term culture of murine erythropoietic progenitor cells in the absence of an adherent layer

Françoise Wendling
Mona M. Shreeve
Arthur A. Axelrad
Research13 Oct 1983
Nature

Volume: 305, P: 625-627
A rapid change in magma plumbing taps porphyry copper deposit-forming magmas

Lawrence C. Carter
Simon R. Tapster
Daniel B. Parvaz
ResearchOpen Access14 Oct 2022
Scientific Reports

Volume: 12, P: 1-20
Modulators and milieu in preretinal neovascularisation

Mike Boulton
Bharti Patel
David McLeod
Research01 Nov 1992
Eye

Volume: 6, P: 560-565
A frame shift mutation in the PMP22 gene in hereditary neuropathy with liability to pressure palsies

Garth A. Nicholson
Linda J. Valentijn
Frank Baas
Research01 Mar 1994
Nature Genetics

Volume: 6, P: 263-266
A specific inhibitor of the ran1⁺ protein kinase regulates entry into meiosis in Schizosaccharomyces pombe

Maureen McLeod
David Beach
Research07 Apr 1988
Nature

Volume: 332, P: 509-514
Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone

David V. Goeddel
Herbert L. Heyneker
Peter H. Seeburg
Research01 Oct 1979
Nature

Volume: 281, P: 544-548
Non-vascular vitreoretinopathy: The cells and the cellular basis of contraction

Ian Grierson
Ank Mazure
David Wong
Research01 Nov 1996
Eye

Volume: 10, P: 671-684
Female plasticity tends to reduce sexual conflict

Evolutionary sexual conflict often occurs after copulation within the female body, allowing the female to respond flexibly to the male strategy. Here, theoretical results show that this female plasticity reduces levels of sexual conflict and prevents runaway selection.

David V. McLeod
Troy Day
Research13 Feb 2017
Nature Ecology & Evolution

Volume: 1, P: 1-4
Ancient DNA reveals that bowhead whale lineages survived Late Pleistocene climate change and habitat shifts

The response of marine species to the Pleistocene climate change is largely unknown. Foote et al. find that the bowhead whale tracked shifting habitat at the end of the Pleistocene and increased in effective population size as suitable habitat and population connectivity increased.

Andrew D. Foote
Kristin Kaschner
M Thomas P. Gilbert
Research09 Apr 2013
Nature Communications

Volume: 4, P: 1-7
Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse

David A. Williams
Ihor R. Lemischka
Richard C. Mulligan
Research09 Aug 1984
Nature

Volume: 310, P: 476-480
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Epigenetic memories and the evolution of infectious diseases

The virulence of some infectious diseases seems to depend on the sex of the host the infection came from, as well as that of the current host. Here, McLeod et al. develop an epidemiological model to investigate the evolution of virulence when pathogens can retain epigenetic memories of their previous host.

David V. McLeod
Geoff Wild
Francisco Úbeda
ResearchOpen Access13 Jul 2021
Nature Communications

Volume: 12, P: 1-13
X-ray observations of the 5 March 1979 γ-burst field

David J. Helfand
Knox S. Long
Research06 Dec 1979
Nature

Volume: 282, P: 589-591
Palaeoenvironmental trends in the history of trace fossils

David J. Bottjer
Mary L. Droser
David Jablonski
Research19 May 1988
Nature

Volume: 333, P: 252-255
Molecular genetic approaches to the analysis of human ophthalmic disease

David N Cooper
Marcelle Jay
Barrie Jay
Research01 Nov 1987
Eye

Volume: 1, P: 699-721
Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut

Ellis J. Neufeld
David G. Skalnik
Stuart H. Orkin
Research01 Apr 1992
Nature Genetics

Volume: 1, P: 50-55
Abnormal lung development and cleft palate in mice lacking TGF–β3 indicates defects of epithelial–mesenchymal interaction

Vesa Kaartinen
Jan Willem Voncken
John Groffen
Research01 Dec 1995
Nature Genetics

Volume: 11, P: 415-421
Interpretation of solar-cycle variability in high-degree p-mode frequencies

David J. Evans
B. Roberts
Research16 Jan 1992
Nature

Volume: 355, P: 230-232
Genome sequence of the Brown Norway rat yields insights into mammalian evolution

Richard A. Gibbs
George M. Weinstock
Francis Collins
Research01 Apr 2004
Nature

Volume: 428, P: 493-521
Schistosomes in the Persian Gulf: novel molecular data, host associations, and life-cycle elucidations

Maral Khosravi
David W. Thieltges
Simona Georgieva
ResearchOpen Access05 Aug 2022
Scientific Reports

Volume: 12, P: 1-12
Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16
Inverted Vascular Bundles in the Leaf of the Thurniaceae

DAVID F. CUTLER
Research15 Jun 1963
Nature

Volume: 198, P: 1111-1112
Photoperiodic Control of the Maintenance and Termination of Larval Diapause in Chironomus tentans

WOLFGANG ENGLEMANN
DAVID G. SHAPPIRIO
Research01 Jul 1965
Nature

Volume: 207, P: 548-549
Three subgroups of patients from the United Kingdom with Leber hereditary optic neuropathy

David A Mackey
Research01 Jul 1994
Eye

Volume: 8, P: 431-436
Possible role of climate in the collapse of Classic Maya civilization

David A. Hodell
Jason H. Curtis
Mark Brenner
Research01 Jun 1995
Nature

Volume: 375, P: 391-394
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Kyle Gaulton, Mark McCarthy, Andrew Morris and colleagues report fine mapping and genomic annotation of 39 established type 2 diabetes susceptibility loci. They find that the set of potential causal variants is enriched for overlap with FOXA2 binding sites in human islet and liver cells, and they show that a likely causal variant near MTNR1B increases FOXA2-bound enhancer activity, providing a molecular mechanism to explain the effect of this locus on disease risk.

Kyle J Gaulton
Teresa Ferreira
Andrew P Morris
Research09 Nov 2015
Nature Genetics

Volume: 47, P: 1415-1425
20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway

Yukiko M. Yamashita
Yukinobu Nakaseko
Mitsuhiro Yanagida
Research21 Nov 1996
Nature

Volume: 384, P: 276-279
The heat shock response of E. coli is regulated by changes in the concentration of σ³²

David B. Straus
William A. Walter
Carol A. Gross
Research24 Sept 1987
Nature

Volume: 329, P: 348-351
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Both rare and common variants contribute to the aetiology of complex traits such as type 2 diabetes (T2D). Here, the authors examine the effect of coding variation on glycaemic traits and T2D, and identify low-frequency variation in GLP1Rsignificantly associated with these traits.

Jennifer Wessel
Audrey Y Chu
Mark O Goodarzi
ResearchOpen Access29 Jan 2015
Nature Communications

Volume: 6, P: 1-16
Increased UV-B penetration in a lake owing to drought-induced acidification

Norman D. Yan
Wendel Keller
Peter J. Dillon
Research09 May 1996
Nature

Volume: 381, P: 141-143
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Exome sequencing and copy number analysis are used to define genomic aberrations in early sporadic pancreatic ductal adenocarcinoma; among the findings are mutations in genes involved in chromatin modification and DNA damage repair, and frequent and diverse somatic aberrations in genes known as embryonic regulators of axon guidance.

Andrew V. Biankin
Nicola Waddell
Sean M. Grimmond
Research24 Oct 2012
Nature

Volume: 491, P: 399-405
Challenges in ophthalmic pathology: The vitreoretinal membrane biopsy

Paul Hiscott
David Wong
Ian Grierson
Reviews01 Jul 2000
Eye

Volume: 14, P: 549-559
Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

Tissue fibrosis is a major contributor to mortality in the developed world. Here, the authors identify a genetic variant in the intronic region of interferon-λ4 that is a strong predictor of hepatic inflammation and fibrosis, independent of liver disease aetiology

Mohammed Eslam
Ahmed M. Hashem
Rosanna Santaro
ResearchOpen Access05 Mar 2015
Nature Communications

Volume: 6, P: 1-10
Haplotype-based inference of recent effective population size in modern and ancient DNA samples

The authors introduce a new computational method, HapNe, for inferring the recent effective size of human populations. HapNe does not require high-quality genotype data, making it suitable for the study of ancient DNA samples.

Romain Fournier
Zoi Tsangalidou
Pier Francesco Palamara
ResearchOpen Access01 Dec 2023
Nature Communications

Volume: 14, P: 1-13
Structural insight into the role of the ribosomal tunnel in cellular regulation

Rita Berisio
Frank Schluenzen
Ada Yonath
Research31 Mar 2003
Nature Structural & Molecular Biology

Volume: 10, P: 366-370
Infective endophthalmitis following vitreoretinal surgery

Annette S Bacon
Charles R Davison
John K G Dart
Research01 Jul 1993
Eye

Volume: 7, P: 529-534
The vitreous

David McLeod
Editorial01 Nov 1992
Eye

Volume: 6, P: vii-viii
Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial

Lindsay B. Kilburn
Dong-Anh Khuong-Quang
Karsten Nysom
Amendments and CorrectionsOpen Access16 Apr 2025
Nature Medicine

Volume: 31, P: 2454
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C

Chronic Hepatitis C infection is associated with a broad spectrum of liver pathologies, ranging from inflammation to fibrosis and liver cancer. Here Thabet et al. identified a polymorphism in the gene MBOAT7 that is associated with increased hepatic inflammation and higher risk of fibrosis development and progression.

Khaled Thabet
Anastasia Asimakopoulos
Rosanna Santaro
ResearchOpen Access15 Sept 2016
Nature Communications

Volume: 7, P: 1-8
Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

Eliana Mariño
James L Richards
Charles R Mackay
Amendments and Corrections18 Oct 2017
Nature Immunology

Volume: 18, P: 1271
Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

Eliana Mariño
James L Richards
Charles R Mackay
Amendments and Corrections19 Jul 2017
Nature Immunology

Volume: 18, P: 951
Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

An integrated analysis of de novo and inherited coding variants in 42,607 individuals with autism spectrum disorder identifies 60 risk genes of which five have not previously been associated with neurodevelopmental disorders.

Xueya Zhou
Pamela Feliciano
Wendy K. Chung
ResearchOpen Access18 Aug 2022
Nature Genetics

Volume: 54, P: 1305-1319
Effects of epistasis and recombination between vaccine-escape and virulence alleles on the dynamics of pathogen adaptation

Modelling shows that vaccines that reduce infection or hasten infection clearance generate positive epistasis between vaccine-escape and virulence alleles, whereas vaccines that reduce virulence generate negative epistasis. High rates of recombination also affect how selection acts on both alleles.

David V. McLeod
Sylvain Gandon
Research18 Apr 2022
Nature Ecology & Evolution

Volume: 6, P: 786-793
Relationship between Brain Blood Flow and Carotid Arterial Flow in the Sheep Fetus

Frank Van Bel
Christine Roman
Abraham M Rudolph
Research01 Mar 1994
Pediatric Research

Volume: 35, P: 329-333
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Protein arginine methyltransferases (PRMTs) are increasingly recognized as potential therapeutic targets but PRMT7 remains an understudied member of this enzyme family. Here, the authors develop a chemical probe for PRMT7 and apply it to elucidate the role of PRMT7 in the cellular stress response.

Magdalena M. Szewczyk
Yoshinori Ishikawa
Dalia Barsyte-Lovejoy
ResearchOpen Access14 May 2020
Nature Communications

Volume: 11, P: 1-15
Vitreous detachment and the posterior hyaloid membrane: A clinicopathological study

Martin P Snead
David R J Snead
John D Scott
Research01 Mar 1994
Eye

Volume: 8, P: 204-209
Management of day-surgery patients with cataract attending a peripheral ophthalmic clinic

Karen Rose
Heather Waterman
Andrew Tullo
Research01 Jan 1999
Eye

Volume: 13, P: 71-75
Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR

David Ng
Nalin Thakker
Leslie G Biesecker
Research07 Mar 2004
Nature Genetics

Volume: 36, P: 411-416
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

Whole-genome sequencing, transcriptome sequencing and single-cell analysis of primary and metastatic pancreatic adenocarcinoma identify molecular subtypes and intratumor heterogeneity.

Michelle Chan-Seng-Yue
Jaeseung C. Kim
Faiyaz Notta
Research13 Jan 2020
Nature Genetics

Volume: 52, P: 231-240

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