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Showing 1–3 of 3 results
Advanced filters: Author: David M. Lubaroff Clear advanced filters

  • In this Review, Geary and colleagues discuss the potential mechanisms of action for all prostate cancer vaccines that trigger cytotoxic-T-lymphocyte-mediated responses and have reached clinical trials. They consider ways in which key immune events are likely to affect the efficacy of each vaccine and consider how information regarding these potential mechanisms can be exploited for future combinatorial treatments.

    • Sean M. Geary
    • Caitlin D. Lemke
    • Aliasger K. Salem
    Reviews
    Nature Reviews Urology
    Volume: 10, P: 149-160

  • This article provides a comprehensive overview of the recent advances in the development and use of humanized mice. The authors consider the remaining challenges and the potential for new advances in our understanding of human immunology through the use of these mice.

    • Leonard D. Shultz
    • Michael A. Brehm
    • Dale L. Greiner
    Reviews
    Nature Reviews Immunology
    Volume: 12, P: 786-798

  • The development of humanized mice over the past few decades has enabled the examination of human haematopoiesis, immunity to infectious diseases, cancer and autoantibodies in mice. But are these mice the key to translational research or is more work required?

    • Leonard D. Shultz
    • Fumihiko Ishikawa
    • Dale L. Greiner
    Reviews
    Nature Reviews Immunology
    Volume: 7, P: 118-130