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Showing 1–2 of 2 results
Advanced filters: Author: Davide Silingardi Clear advanced filters
  • miR-132/212 has been implicated in ocular dominance plasticity during the critical period. Here the authors show that miR-132/212 regulates the expression of genes involved in visual cortex maturation, and that mice lack miR-132/212 show deficits in binocular matching of orientation preferences, which leads to impaired depth perception.

    • Raffaele Mazziotti
    • Laura Baroncelli
    • Tommaso Pizzorusso
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12
  • This study shows that ocular dominance plasticity (ODP) is accompanied by changes to DNA methylation at specific genes in the mouse visual cortex. The authors also show that pharmacological inhibition of the DNA methylation process can alter the functional consequence of ODP.

    • Paola Tognini
    • Debora Napoli
    • Tommaso Pizzorusso
    Research
    Nature Neuroscience
    Volume: 18, P: 956-958