Nature Search

Biotechnology education for school-age students

Dean Madden
Research01 Jan 1998
Nature Biotechnology

Volume: 16, P: 98
Seasonal predictability of the dominant surface ozone pattern over China linked to sea surface temperature

Yuan Chen
Dean Chen
Yongwen Zhang
ResearchOpen Access15 Jan 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-8
Application of an artificial neural network to predict specific class I MHC binding peptide sequences

Mariusz Milik
Dean Sauer
Charles A. Glass
Research01 Aug 1998
Nature Biotechnology

Volume: 16, P: 753-756
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent risk loci. Comparisons with other psychiatric disorders and candidate gene analyses provide new insights into major depressive disorder.

Naomi R. Wray
Stephan Ripke
Patrick F. Sullivan
Research26 Apr 2018
Nature Genetics

Volume: 50, P: 668-681
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Environmental influences during prenatal development may have implications for health and disease later in life. Here, Czamara et al. assess DNA methylation in cord blood from new-born under various models including environmental and genetic effects individually and their additive or interaction effects.

Darina Czamara
Gökçen Eraslan
Elisabeth B. Binder
ResearchOpen Access11 Jun 2019
Nature Communications

Volume: 10, P: 1-18
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Depression is correlated with many brain-related traits. Here, Shen et al. perform phenome-wide association studies of a depression polygenic risk score (PRS) and find associations with 51 behavioural and 26 neuroimaging traits which are further followed up on using Mendelian randomization and mediation analyses.

Xueyi Shen
David M. Howard
Andrew M. McIntosh
ResearchOpen Access08 May 2020
Nature Communications

Volume: 11, P: 1-16
Identification of common genetic risk variants for autism spectrum disorder

A genome-wide-association meta-analysis of 18,381 austim spectrum disorder (ASD) cases and 27,969 controls identifies five risk loci. The authors find quantitative and qualitative polygenic heterogeneity across ASD subtypes.

Jakob Grove
Stephan Ripke
Anders D. Børglum
Research25 Feb 2019
Nature Genetics

Volume: 51, P: 431-444
The structure and function of glutamate receptor ion channels

Dean R. Madden
Reviews01 Feb 2002
Nature Reviews Neuroscience

Volume: 3, P: 91-101
Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei

Eighty-nine percent of the Trypanosoma brucei proteome is mapped using fluorescence microscopy and cell lines expressing endogenously tagged proteins, and presented in a resource for the community named TrypTag.org.

Karen Billington
Clare Halliday
Keith Gull
ResearchOpen Access20 Feb 2023
Nature Microbiology

Volume: 8, P: 533-547
New light on an open-and-shut case

In the brain, neurotransmitter-receptor binding represents the moment of stereochemical recognition in which one neuron senses the signal sent by another. Submillisecond time-resolved FTIR spectroscopy now provides a first glimpse of the generative protein-ligand interactions that lead to glutamate receptor ion channel activation.

Dean R Madden
News & Views01 Nov 2005
Nature Chemical Biology

Volume: 1, P: 317-319
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Azmeraw T. Amare
Klaus Oliver Schubert
Bernhard T. Baune
Research16 Mar 2020
Molecular Psychiatry

Volume: 26, P: 2457-2470
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Jonathan R. I. Coleman
Wouter J. Peyrot
Gerome Breen
Research23 Jan 2020
Molecular Psychiatry

Volume: 25, P: 1430-1446
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Simone de Jong et al. examine the balance of common and rare risk for psychiatric disorders in a large family with high incidence of Bipolar Disorder and Major Depressive Disorder. They find that increased polygenic risk over generations could be partially due to assortative mating, which may explain the observation of anticipation in mood disorders.

Simone de Jong
Mateus Jose Abdalla Diniz
Gerome Breen
ResearchOpen Access08 Oct 2018
Communications Biology

Volume: 1, P: 1-10
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Till F. M. Andlauer
Jose Guzman-Parra
Marcella Rietschel
ResearchOpen Access11 Nov 2019
Molecular Psychiatry

Volume: 26, P: 1286-1298
Flow-Induced Responses in Piglet Isolated Cerebral Arteries

Larissa A Shimoda
Nan A Norins
Jane A Madden
Research01 Apr 1996
Pediatric Research

Volume: 39, P: 574-583
Is there a role for triclosan/copolymer toothpaste in the management of periodontal disease?

A. Blinkhorn
P. M. Bartold
G. J. Seymour
Research08 Aug 2009
British Dental Journal

Volume: 207, P: 117-125
Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Jonathan R. I. Coleman
Wouter J. Peyrot
Gerome Breen
Amendments and Corrections18 May 2020
Molecular Psychiatry

Volume: 26, P: 5465

Search

Biotechnology education for school-age students

Seasonal predictability of the dominant surface ozone pattern over China linked to sea surface temperature

Application of an artificial neural network to predict specific class I MHC binding peptide sequences

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Identification of common genetic risk variants for autism spectrum disorder

The structure and function of glutamate receptor ion channels

Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei

New light on an open-and-shut case

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Flow-Induced Responses in Piglet Isolated Cerebral Arteries

Is there a role for triclosan/copolymer toothpaste in the management of periodontal disease?

Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

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