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Showing 1–3 of 3 results
Advanced filters: Author: Deborah Nejman Clear advanced filters

  • HLA peptidomic analysis identifies recurrent intracellular bacteria-derived peptides presented on HLA-I and HLA-II molecules in melanoma tumours, revealing how bacteria can modulate immune functions and responses to cancer therapies.

    • Shelly Kalaora
    • Adi Nagler
    • Yardena Samuels
    Research
    Nature
    Volume: 592, P: 138-143

  • High levels of Fusobacterium nucleatum have been associated with poor overall survival in patients with colorectal and esophageal cancer. Here, the authors show that F. nucleatum is abundant in breast cancer samples and that the colonization by F. nucleatum accelerates tumor growth and metastasis in preclinical breast cancer models.

    • Lishay Parhi
    • Tamar Alon-Maimon
    • Gilad Bachrach
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • A genome-wide analysis of methylated DNA from human embryonic stem cells and adult tissues provides a comprehensive view of unmethylated regions and leads to the identification of sequence motifs that can predict whether a region escapes de novo methylation. This algorithm is used to identify novel, non-CpG unmethylated regions, including intragenic and tissue-specific ones.

    • Ravid Straussman
    • Deborah Nejman
    • Howard Cedar
    Research
    Nature Structural & Molecular Biology
    Volume: 16, P: 564-571