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Showing 1–3 of 3 results
Advanced filters: Author: Deborah Sementa Clear advanced filters

  • Here the authors design tripeptides that form dynamic soluble dispersions and undergo phase separation upon drying to assemble into porous particles. This evaporation-driven emulsification can be harnessed to encapsulate and stabilize biomolecules.

    • Dhwanit R. Dave
    • Salma Kassem
    • Rein V. Ulijn
    ResearchOpen Access
    Nature Materials
    Volume: 24, P: 1465-1475

  • Fluorescence-based oligonucleotide probes, also known as molecular beacons (MBs), are popular for detecting nucleic acids with high specificity. Here, the authors demonstrate self-sequestration of MB-based biosensors and target strands within peptide-based coacervates, increasing local concentrations and significantly increasing the sensitivity and kinetics of the DNA biosensors.

    • Christopher M. Green
    • Deborah Sementa
    • Sebastián A. Díaz
    ResearchOpen Access
    Communications Chemistry
    Volume: 7, P: 1-9

  • Living systems create exceptional materials from simple amino acid building blocks. This Review explores how a systems-based approach — considering peptide, solvent and environment, and integrating computation and experimentation — can unlock peptide sequence space as a universal materials assembly code, enabling designs beyond biology’s natural scope.

    • Kübra Kaygisiz
    • Deborah Sementa
    • Rein V. Ulijn
    Reviews
    Nature Reviews Materials
    Volume: 10, P: 449-472