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Showing 1–4 of 4 results
Advanced filters: Author: Deepak A. Kaji Clear advanced filters
  • Adenosine-to-inosine editing is a form of RNA modification observed in the human brain transcriptome. Here the authors question the accuracy of utilizing postmortem samples to reflect the RNA biology of living brains. This is due to significant differences in adenosine-to-inosine editing between living and postmortem brain tissues, with most sites exhibiting higher editing levels postmortem.

    • Miguel Rodriguez de los Santos
    • Brian H. Kopell
    • Michael S. Breen
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15
  • The inclusion of polygenic risk scores does not improve the performance of standard-of-care predictive models of disease outcomes in patients with psychosis.

    • Isotta Landi
    • Deepak A. Kaji
    • Alexander W. Charney
    Research
    Nature Medicine
    Volume: 27, P: 1576-1581
  • The transcriptional regulators underlying the induction and differentiation of dense connective tissues remain largely unknown. Here the authors generate tendon and fibrocartilage cells from mouse embryonic stem cells and apply scRNA-seq to identify molecular regulation of the cell fate switch between these lineages.

    • Deepak A. Kaji
    • Angela M. Montero
    • Alice H. Huang
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16