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Showing 1–5 of 5 results

Advanced filters: Author: Denise Traxler Clear advanced filters

Preclinical development of a miR-132 inhibitor for heart failure treatment

miR-132 was shown to drive pathological cardiac remodeling, a hallmark of heart failure. Here, the authors show that an antisense inhibitor of miR-132 has favourable pharmacokinetics, safety-tolerability and preclinical efficacy in mouse and porcine models of heart failure.

Ariana Foinquinos
Sandor Batkai
Thomas Thum
ResearchOpen Access31 Jan 2020
Nature Communications

Volume: 11, P: 1-10
Safety and tolerability of topically administered autologous, apoptotic PBMC secretome (APOSEC) in dermal wounds: a randomized Phase 1 trial (MARSYAS I)

Elisabeth Simader
Denise Traxler
Hendrik Jan Ankersmit
ResearchOpen Access24 Jul 2017
Scientific Reports

Volume: 7, P: 1-8
microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data

microbeMASST is a tool to associate known and unknown metabolites to microbial producers leveraging untargeted metabolomics data.

Simone Zuffa
Robin Schmid
Pieter C. Dorrestein
ResearchOpen Access05 Feb 2024
Nature Microbiology

Volume: 9, P: 336-345
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

GNPS is an open-access community-curated analysis platform for sharing natural product mass spectrometry data that enables continuous, automatic reanalysis of deposited 'living' data sets.

Mingxun Wang
Jeremy J Carver
Nuno Bandeira
Reviews09 Aug 2016
Nature Biotechnology

Volume: 34, P: 828-837
Different pro-angiogenic potential of γ-irradiated PBMC-derived secretome and its subfractions

Tanja Wagner
Denise Traxler
Michael Mildner
ResearchOpen Access20 Dec 2018
Scientific Reports

Volume: 8, P: 1-15