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Showing 1–2 of 2 results
Advanced filters: Author: Devbarna Sinha Clear advanced filters

  • BET inhibitors that target bromodomain chromatin readers such as BRD4 are being explored as potential therapeutics in cancer; here, in a MLL–AF9 mouse leukaemia model, resistance to BET inhibitors is shown to emerge from leukaemia stem cells, and be partly due to increased Wnt/β-catenin signalling.

    • Chun Yew Fong
    • Omer Gilan
    • Mark A. Dawson
    Research
    Nature
    Volume: 525, P: 538-542