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Showing 1–2 of 2 results
Advanced filters: Author: Devdatt Dubhashi Clear advanced filters

  • Design of de novo synthetic regulatory DNA is a promising avenue to control gene expression in biotechnology and medicine. Here the authors present EspressionGAN, a generative adversarial network that uses genomic and transcriptomic data to generate regulatory sequences.

    • Jan Zrimec
    • Xiaozhi Fu
    • Aleksej Zelezniak
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17

  • Plasmids are present in many bacteria and are often transferred between different species causing horizontal gene transfer. By comparing the sequences of 25 plasmid DNA backbones, the authors show that homologous recombination is prevalent in plasmids and that the plasmids have adapted to persist in different host bacteria.

    • Peter Norberg
    • Maria Bergström
    • Malte Hermansson
    ResearchOpen Access
    Nature Communications
    Volume: 2, P: 1-11