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Showing 1–2 of 2 results
Advanced filters: Author: Dharmendra Dheeman Clear advanced filters

  • The presence of the gene encoding the solute binding protein TphC has been shown to permit the uptake of terephthalate (TPA), which is the breakdown product of Polyethylene terephthalate (PET) plastic. Here the authors present a structural characterization of TphC in both open and TPA-bound closed conformations.

    • Trishnamoni Gautom
    • Dharmendra Dheeman
    • Neil Dixon
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Nadar, Chen, Dheeman et al. show that arsinothricin, an arsenic-containing non- proteinogenic amino acid analog of glutamate, is an effective broad-spectrum antibiotic through inhibition of glutamine synthetase. This study suggests a possibility of developing a new class of antimicrobials that thwart microbial resistance to arsinothricin.

    • Venkadesh Sarkarai Nadar
    • Jian Chen
    • Masafumi Yoshinaga
    ResearchOpen Access
    Communications Biology
    Volume: 2, P: 1-12