Nature Search

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging

Using a zebrafish-based screen, Civiletto and colleagues identify the herb-derived metabolites thymol and carvacrol as activators of autophagy and mitophagy, demonstrating their therapeutic potential in C. elegans and mouse models.

Gabriele Civiletto
Dario Brunetti
Philipp Gut
ResearchOpen Access24 Sept 2025
Nature Aging

P: 1-19
Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes

The photoluminescence properties of carbon nanotubes are sensitive to molecular adsorption. By studying the response of a pair of single-wall carbon nanotubes, researchers have now shown that analytes of biological interest can be identified and measured in real-time within living cells.

Daniel A. Heller
Hong Jin
Michael S. Strano
Research14 Dec 2008
Nature Nanotechnology

Volume: 4, P: 114-120
Digging deeper: methodologies for high-content phenotyping in Caenorhabditis elegans

Deep phenotyping can reveal how genetics, environment and stochasticity affect the development, physiology and behavior of an organism. In this Review, Dhaval S. Patel, Nan Xu and Hang Lu outline the technological and analytical developments that have enabled deep-phenotyping studies in Caenorhabditis elegans.

Dhaval S. Patel
Nan Xu
Hang Lu
Reviews19 Jun 2019
Lab Animal

Volume: 48, P: 207-216
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
ResearchOpen Access20 Apr 2020
Nature Medicine

Volume: 26, P: 750-759
Correction: Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial

Sunil S. Patel
David R. Lally
Arshad M. Khanani
Amendments and CorrectionsOpen Access26 May 2023
Eye

Volume: 37, P: 3705
Unravelling the secrets of lesser florican: a study of their home range and habitat use in Gujarat, India

Mohan Ram
Devesh Gadhavi
Dhaval Devaliya
ResearchOpen Access04 Nov 2023
Scientific Reports

Volume: 13, P: 1-14
Targeting allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) to identify natural product inhibitors via structure-based computational approach

Nisarg Rana
Dhaval Patel
Anu Manhas
ResearchOpen Access23 Oct 2023
Scientific Reports

Volume: 13, P: 1-22
Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial

Sunil S. Patel
David R. Lally
Arshad M. Khanani
ResearchOpen Access24 Mar 2023
Eye

Volume: 37, P: 3551-3557
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
Amendments and CorrectionsOpen Access02 Jul 2020
Nature Medicine

Volume: 26, P: 1308
Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth

Sahar Shekoohi
Santhanasabapathy Rajasekaran
Stephan N. Witt
ResearchOpen Access04 Mar 2021
Scientific Reports

Volume: 11, P: 1-15
An automated platform to monitor long-term behavior and healthspan in Caenorhabditis elegans under precise environmental control

Kim N. Le, Mei Zhan et al. develop an automated microfluidic-based system, HeALTH, which provides spatiotemporal environmental control and allows for long-term behavioral monitoring. Using Caenorhabditis elegans they demonstrate the robustness of this platform for health and lifespan studies, and highlight its adaptability to other model systems.

Kim N. Le
Mei Zhan
Hang Lu
ResearchOpen Access10 Jun 2020
Communications Biology

Volume: 3, P: 1-13
Multidimensional analyses reveal modulation of adaptive and innate immune subsets by tuberculosis vaccines

Virginie Rozot and Elisa Nemes et al. report comprehensive profiling of immune responses from participants in a recent clinical trial of the H4:IC31 and BCG vaccines against Mycobacterium tuberculosis infection. Using a novel analysis platform, they uncover complex vaccine-induced modulation of different immune cell subsets.

Virginie Rozot
Elisa Nemes
Noncedo Xoyana
ResearchOpen Access09 Oct 2020
Communications Biology

Volume: 3, P: 1-12

Search

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging

Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes

Digging deeper: methodologies for high-content phenotyping in Caenorhabditis elegans

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Correction: Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial

Unravelling the secrets of lesser florican: a study of their home range and habitat use in Gujarat, India

Targeting allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) to identify natural product inhibitors via structure-based computational approach

Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial

Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth

An automated platform to monitor long-term behavior and healthspan in Caenorhabditis elegans under precise environmental control

Multidimensional analyses reveal modulation of adaptive and innate immune subsets by tuberculosis vaccines

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