The crystal structure of the maltose transporter, in complex with its periplasmic maltose-binding protein, at 2.8 Å resolution is presented. Because both ATP and maltose are bound and a mutation that prevents ATP hydrolysis has been introduced, the complex has been captured in an intermediate state and a mechanism for maltose transport proposed.
- Michael L. Oldham
- Dheeraj Khare
- Jue Chen
