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Advanced filters: Author: Diankun Yu Clear advanced filters

Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1

Microglia-derived IGF1 promotes the proliferation of GABAergic progenitors and neuroblasts in the human medial ganglionic eminence, contributing to the extended production of GABAergic neurons and an expanded cognitive capacity in the human brain.

Diankun Yu
Samhita Jain
Xianhua Piao
ResearchOpen Access06 Aug 2025
Nature

P: 1-11
BK channel deacetylation by SIRT1 in dentate gyrus regulates anxiety and response to stress

Diankun Yu et al. show that deacetylase SIRT1 rapidly modulates synaptic properties of the dentate gyrus granule cells and anxiety behaviors through deacetylation of BK channel α subunits. This study provides mechanistic insight into how SIRT1 regulates fight-or-flight stress response.

Diankun Yu
Damek R. Homiack
Laura A. Schrader
ResearchOpen Access28 Jun 2018
Communications Biology

Volume: 1, P: 1-14
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy

Lingfeng Yu
Gentao Fan
Guangxin Zhou
ResearchOpen Access22 Sept 2023
Cell Death & Disease

Volume: 14, P: 1-16

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