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Showing 1–3 of 3 results
Advanced filters: Author: Dibyendu Mondal Clear advanced filters

  • Catalytic enantioselective halocyclization of alkenes is an important bond forming tool and a key step in natural product biosynthesis, but so far no examples of the enzymatic counterpart of this reaction on simple achiral olefins have been reported. Here, the authors describe examples of engineered flavin-dependent halogenases that catalyze halolactonization of olefins with high enantioselectivity and near-native catalytic activity.

    • Dibyendu Mondal
    • Brian F. Fisher
    • Jared C. Lewis
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-7

  • The applicability of protein fibrils as functional biomaterials is limited due to low scalability of production process, slow kinetics, and requirement of expensive purified proteins. Here, instantaneous production of protein fibrils from egg white proteome using cholinium tosylate as a fibrillation agent is shown, with the obtained fibrils displaying enhanced mechanical stiffness and cytocompatibility.

    • Pankaj Bharmoria
    • Dibyendu Mondal
    • Mara G. Freire
    ResearchOpen Access
    Communications Materials
    Volume: 1, P: 1-13