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Showing 1–2 of 2 results
Advanced filters: Author: Dilara Özdemir Clear advanced filters
  • α-ketoglutarate (αKG) is an intermediate in the tricarboxylic acid cycle that is required in the nucleus for genomic DNA demethylation by Tet3. Here, the authors show that the enzyme glutamate dehydrogenase, which converts glutamate to αKG, is redirected from the mitochondria to the nucleus.

    • Franziska R. Traube
    • Dilara Özdemir
    • Thomas Carell
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13
  • Artificial intelligence has become popular as a cancer classification tool, but there is distrust of such systems due to their lack of transparency. Here, the authors develop an explainable AI system which produces text- and region-based explanations alongside its classifications which was assessed using clinicians’ diagnostic accuracy, diagnostic confidence, and their trust in the system.

    • Tirtha Chanda
    • Katja Hauser
    • Titus J. Brinker
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17