The dynamics of microglia states adjacent to or far from amyloid-beta plaques are unclear. Here the authors show that non-plaque-associated microglia modulate the cell population expansion in response to amyloid deposition, and Csf1 signaling regulates their transition to the amyloid-associated state.
- Alberto Ardura-Fabregat
- Lance Fredrick Pahutan Bosch
- Marco Prinz
