Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–13 of 13 results
Advanced filters: Author: Dimitri P Mikhailidis Clear advanced filters

  • Much could be gained by a reform of the system by which doctoral degrees are awarded, not least because of the single European market, due in 1993.

    • Lars H. Breimer
    • Dimitri P. Mikhailidis
    Comments & Opinion
    Nature
    Volume: 353, P: 789-790

  • Statins are effective for cardiovascular disease prevention but have recently been associated with an increased risk of new-onset diabetes mellitus. However, until this association is confirmed, treatment discontinuation is not advisable. Lifestyle measures and treatment of risk factors that often cluster with dyslipidemia could ameliorate this potential adverse effect of statins.

    • Vassilios G. Athyros
    • Dimitri P. Mikhailidis
    News & Views
    Nature Reviews Endocrinology
    Volume: 8, P: 133-134

  • Two recent studies suggest that periprocedural statin administration can prevent contrast-induced acute kidney injury in cardiac patients undergoing percutaneous coronary intervention and in renal patients undergoing angiography, with or without intervention. These studies support the routine administration of potent statins before contrast media infusion in these vulnerable patients.

    • Dimitri P. Mikhailidis
    • Vasilios G. Athyros
    News & Views
    Nature Reviews Nephrology
    Volume: 10, P: 8-9

  • A new report examines trends in caloric and fat intake—known modifiers of cardiovascular risk—among statin users and non-users. As statins are the most effective hypolipidaemic agents currently used to prevent cardiovascular disease, it is important to understand how statin treatment affects dietary attitude.

    • Vasilios G. Athyros
    • Dimitri P. Mikhailidis
    News & Views
    Nature Reviews Endocrinology
    Volume: 10, P: 450-451

  • The new ACC/AHA guidelines on treatment of blood cholesterol focus on intensity of statin therapy rather than target levels of lipids. Early studies show substantial reductions in LDL-cholesterol level with antibodies against PCSK9. MicroRNA silencing and gene-repair techniques to treat dyslipidaemia are promising strategies under development.

    • Dimitri P. Mikhailidis
    • Vasilios G. Athyros
    News & Views
    Nature Reviews Cardiology
    Volume: 11, P: 72-74

  • Toll-like receptors (TLRs) have a key role in the regulation of innate immunity by mediating signal transduction pathways that modulate the expression of proinflammatory cytokines and chemokines. This Review discusses the potential role of TLRs in the pathogenesis of renal conditions such as acute kidney injury, acute glomerulonephritis, and renal transplant rejection. The authors also describe studies that have used pharmacological inhibition of TLR signaling to modify the response to proinflammatory stimuli.

    • Anna Gluba
    • Maciej Banach
    • Jacek Rysz
    Reviews
    Nature Reviews Nephrology
    Volume: 6, P: 224-235

  • Statins might exert diabetogenic effects, potentially increasing insulin resistance and worsening glucose control. However, patients with diabetes mellitus are at high or very high cardiovascular risk and, thus, statin use is strongly recommended. Adding ezetimibe to statins might be helpful in achieving lipid targets and reducing cardiovascular risk without adversely affecting glucose metabolism.

    • Niki Katsiki
    • Dimitri P. Mikhailidis
    News & Views
    Nature Reviews Endocrinology
    Volume: 18, P: 137-138