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Advanced filters: Author: Dimuthu Angage Clear advanced filters

  • Apical membrane antigen-1 (AMA1) is important for Plasmodium parasite invasion, but surface polymorphisms in P. falciparum AMA1 hamper vaccine and antibody development. Here the authors identify a humanised single-domain antibody molecule, an i-body, that binds to AMA1 of all Plasmodium parasites examined and inhibits parasite invasion.

    • Dimuthu Angage
    • Jill Chmielewski
    • Michael Foley
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17