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Advanced filters: Author: Divyesh Patel Clear advanced filters

Transposable elements as tissue-specific enhancers in cancers of endodermal lineage

A comprehensive characterisation of transposable elements (TEs) in cancer is lacking. Here, the authors identify distinct TEs with different genomic features as tissue-specific enhancers in colorectal and liver cancer.

Konsta Karttunen
Divyesh Patel
Biswajyoti Sahu
ResearchOpen Access01 Sept 2023
Nature Communications

Volume: 14, P: 1-19
Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes

Systematic comparative analysis across three cancer types reveals how epigenetic drugs derepress transposable elements via distinct mechanisms influenced by p53 status, offering insights for strategic use of epigenetic therapies in different cancers.

Divyesh Patel
Ville Tiusanen
Biswajyoti Sahu
ResearchOpen Access03 Jul 2025
Communications Biology

Volume: 8, P: 1-18

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Transposable elements as tissue-specific enhancers in cancers of endodermal lineage

Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes

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