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Showing 1–1 of 1 results
Advanced filters: Author: Dmitri Rebatchouk Clear advanced filters
  • Ibrutinib has demonstrated high response rates in B-cell lymphomas but a lot of ibrutinib-treated patients relapse with resistance. This study unified TME-mediatedde novoand acquired drug resistance through B-cell receptor signalling and PI3K-AKT-mTOR axis and provides a combination therapeutic strategy against B-cell malignancies.

    • Xiaohong Zhao
    • Tint Lwin
    • Jianguo Tao
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15