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Showing 1–7 of 7 results

Advanced filters: Author: Dolores D. Mruk Clear advanced filters

A male contraceptive targeting germ cell adhesion

Dolores D Mruk
Ching-Hang Wong
C Yan Cheng
Research29 Oct 2006
Nature Medicine

Volume: 12, P: 1323-1328
A local autocrine axis in the testes that regulates spermatogenesis

A local autocrine axis exists in the testes that regulates spermatogenesis. In this Review, Cheng and Mruk review findings from the past decade that support the presence and reveal the importance of this axis, which is an emerging target for male contraceptive development.

C. Yan Cheng
Dolores D. Mruk
Reviews01 Jul 2010
Nature Reviews Endocrinology

Volume: 6, P: 380-395
A peptide derived from laminin-γ3 reversibly impairs spermatogenesis in rats

The temporal opening and closing of cell–cell junctions at the blood–testis barrier allows the passage of immature germ cells during spermatogenesis. Su and colleagues identify a peptide fragment of the laminin-γ3 chain that disrupts the blood–testis barrier and reversibly impairs spermatogenesis in rats.

Linlin Su
Dolores D. Mruk
C. Yan Cheng
Research13 Nov 2012
Nature Communications

Volume: 3, P: 1-13
Erratum: Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2

Ying Gao
Haiqi Chen
C. Yan Cheng
Amendments and CorrectionsOpen Access26 Jul 2017
Scientific Reports

Volume: 7, P: 1-3
Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43

Nan Li
Dolores D. Mruk
C. Yan Cheng
ResearchOpen Access20 Jul 2016
Scientific Reports

Volume: 6, P: 1-14
Rescue of PFOS-induced human Sertoli cell injury by overexpressing a p-FAK-Y407E phosphomimetic mutant

Haiqi Chen
Ying Gao
C. Yan Cheng
ResearchOpen Access17 Nov 2017
Scientific Reports

Volume: 7, P: 1-15
Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2

Ying Gao
Haiqi Chen
C. Yan Cheng
ResearchOpen Access24 Apr 2017
Scientific Reports

Volume: 7, P: 1-14