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Showing 1–5 of 5 results
Advanced filters: Author: Dominic Gillespie Clear advanced filters

  • Gaining control over crystallization processes is challenging. Herein, the authors describe a protocol for the controlled growth of DNA nanotubes by feedback regulation: the coupling of a reversible bimolecular monomer buffering reaction delivers the optimal monomer concentration and leads to reliable crystal growth in a simple manner.

    • Samuel W. Schaffter
    • Dominic Scalise
    • Rebecca Schulman
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Understanding the heterogeneity of HIV infection, such as in persons with non-suppressible HIV-1 viremia despite adherence to antiretroviral treatment, is crucial to better tailor therapeutic interventions to abrogate HIV-1 persistence.

    • Abbas Mohammadi
    • Behzad Etemad
    • Jonathan Z. Li
    ResearchOpen Access
    Nature Medicine
    Volume: 29, P: 3212-3223

  • Complement factor H (FH) binds complement 3b and promotes the stepwise degradation of C3b to C3d, protecting self cells from being mistakenly recognized as foreign. A previous structure showed how CCP modules 1–4 of FH bind C3b; this study now shows the interaction of CCP modules 19–20 with C3d and builds a model for the interaction of the complete FH molecule with C3b.

    • Hugh P Morgan
    • Christoph Q Schmidt
    • Jonathan P Hannan
    Research
    Nature Structural & Molecular Biology
    Volume: 18, P: 463-470