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Showing 1–4 of 4 results
Advanced filters: Author: Dominik Duelli Clear advanced filters

  • The ability to fuse cells is shared by many viruses. Does cell fusion, by inducing chromosomal instability, for example, link more viruses to cancer development? How can such hypotheses be tested?

    • Dominik Duelli
    • Yuri Lazebnik
    Reviews
    Nature Reviews Cancer
    Volume: 7, P: 968-976

  • Usher syndrome is a congenital form of deafness and vestibular dysfunction characterized by mutations in the USH1C gene encoding harmonin. Michelle L. Hastings and her colleagues show in a mouse model of Usher syndrome that early treatment with antisense oligonucleotides corrects defective pre-mRNA splicing of mutant USH1C, increasing full-length harmonin expression and restoring low-frequency hearing and vestibular function.

    • Jennifer J Lentz
    • Francine M Jodelka
    • Michelle L Hastings
    Research
    Nature Medicine
    Volume: 19, P: 345-350