Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: Dominik Trzupek Clear advanced filters

  • Regulatory T cells maintain immune homeostasis and help control development of autoimmunity and allergy. Arroyo-Hornero et al show that upon prolonged stimulation, regulatory T cells may switch to an immunostimulatory phenotype by upregulating the expression of the co-stimulatory molecule CD70.

    • Rebeca Arroyo Hornero
    • Christos Georgiadis
    • Joanna Hester
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-17

  • Low-dose interleukin-2 is showing promise in the treatment of several autoimmune inflammatory diseases. Here authors map the trajectory of cellular and transcriptional changes in type 1 diabetes patients receiving an interval dosing interleukin-2 regimen, which shows an anti-inflammatory gene expression signature shared by all immune cell types analysed, persisting for at least a month after ending treatment.

    • Jia-Yuan Zhang
    • Fiona Hamey
    • Ricardo C. Ferreira
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17