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Nature Immunology (1)

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The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C⁻ monocytes

Ly6C^– monocytes patrol blood vessels by crawling along uninflamed vasculature. Hedrick and colleagues show that the transcription factor NR4A1 is required for the development and survival of Ly6C^– monocytes.

Richard N Hanna
Leo M Carlin
Catherine C Hedrick
Research03 Jul 2011
Nature Immunology

Volume: 12, P: 778-785

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The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

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The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C⁻ monocytes