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Nature Cell Biology (1)

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A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors

Nerlov and colleagues show that expression of mKitL by cortical vascular endothelial cells is important for DN1 progenitor maintenance, whereas expression of mKitL by cortical thymic epithelial cells is required for maintaining DN2 progenitor cells.

Mario Buono
Raffaella Facchini
Claus Nerlov
Research18 Jan 2016
Nature Cell Biology

Volume: 18, P: 157-167

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A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors

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