Proliferative vitreoretinopathy (PVR) is a vision-threatening response to ocular injury, in which retinal cells secrete tractional, scar-forming proteins. Here, the authors show that antibody blockade of either Annexin A2 or its inducer, macrophage inflammatory protein-1, prevents PVR in mice.
- Min Luo
- Dena Almeida
- Katherine A. Hajjar