The limited solubility, inherent chemical stability, and low reactivity of inorganic phosphates pose hinder their conversion into organophosphates under mild conditions. Here, the authors report a method for the direct conversion of phosphates into P(V)-X reagents via a redox-neutral halogenation process, using cyanuric chloride or cyanuric fluoride as the halogenation reagent.
- Yaling Tian
- Dong-ping Chen
- Zheng-Jun Quan