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Showing 1–50 of 55 results

Advanced filters: Author: Dorothy E Lewis Clear advanced filters

Structure of Vitamin B₁₂: X-ray Crystallographic Evidence on the Structure of Vitamin B₁₂

CLARA BRINK
DOROTHY CROWFOOT HODGKIN
JOHN G. WHITE
Research25 Dec 1954
Nature

Volume: 174, P: 1169-1171
Acute Intravascular Haemolysis and Platelet Behaviour

DOROTHY BUSFIELD
E. G. TOMICH
Research18 May 1968
Nature

Volume: 218, P: 696-697
Fluorinated Pyrimidines, A New Class of Tumour-Inhibitory Compounds

CHARLES HEIDELBERGER
N. K. CHAUDHURI
J. SCHEINER
Research30 Mar 1957
Nature

Volume: 179, P: 663-666
Mobilization of Transduced Tetracycline Resistance by the Δ Transfer Factor in Salmonella typhimurium and S. typhi

E. S. ANDERSON
DOROTHY PERRET
Research20 May 1967
Nature

Volume: 214, P: 810-811
Effect of Suspending Medium on Heat Resistance of Spores of Clostridium perfringens

KARL F. WEISS
DOROTHY H. STRONG
Research01 Jul 1967
Nature

Volume: 215, P: 530-531
Effect of Incubation Temperature on the Flagellation of Gram-negative Rods

DOROTHY A. ORR
MARGARET M. TAYLOR
Research04 Dec 1965
Nature

Volume: 208, P: 1017
Effect of d-Gamma-tocopherol on the Incidence of Teratogeny in Vitamin E-deficient Rats

DOROTHY WEI KING
Research21 Nov 1964
Nature

Volume: 204, P: 785-786
Breakpoints in the human T-cell antigen receptor α-chain locus in two T-cell leukaemia patients with chromosomal translocations

William H. Lewis
Effie E. Michalopoulos
Tak W. Mak
Research01 Oct 1985
Nature

Volume: 317, P: 544-546
INFECTIOUS DISEASE FIRST SESSION May 17, 1973, 2:00 P.M. Continental Ballroom 5

Dorothy M Horstmann
Research01 Apr 1973
Pediatric Research

Volume: 7, P: 41-44
Identification of the herpes simplex virus DNA polymerase gene

DOROTHY J. M. PURIFOY
ROBERT B. LEWIS
KENNETH L. POWELL
Research01 Oct 1977
Nature

Volume: 269, P: 621-623
A New Human Blood Group

MARIE CUTBUSH
P. L. MOLLISON
DOROTHY M. PARKIN
Research04 Feb 1950
Nature

Volume: 165, P: 188-189
Insect Parasite of the Pea-Weevil

DOROTHY J. JACKSON
Research08 Mar 1924
Nature

Volume: 113, P: 353-354
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Genome-wide analyses identify 30 independent loci associated with obsessive–compulsive disorder, highlighting genetic overlap with other psychiatric disorders and implicating putative effector genes and cell types contributing to its etiology.

Nora I. Strom
Zachary F. Gerring
Manuel Mattheisen
ResearchOpen Access13 May 2025
Nature Genetics

Volume: 57, P: 1389-1401
Transmission of conformational change in insulin

Cyrus Chothia
Arthur M. Lesk
Dorothy C. Hodgkin
Research01 Apr 1983
Nature

Volume: 302, P: 500-505
… to top

Dorothy A. Miller
Books & Arts11 Feb 1982
Nature

Volume: 295, P: 478
Transcription by single molecules of RNA polymerase observed by light microscopy

Dorothy A. Schafer
Jeff Gelles
Robert Landick
Research01 Aug 1991
Nature

Volume: 352, P: 444-448
Patterns of Cystine Reduction by Fibroblasts from Normal and Cystinotic Children

Beatrice States
Dorothy Harris
Stanton Segal
Research01 May 1977
Pediatric Research

Volume: 11, P: 685-690
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Development of a Clinical Protocol for Hepatic Gene Transfer: Lessons Learned in Preclinical Studies

Fred D Ledley
Mark R Adams
Savio L C Woo
Research01 Apr 1993
Pediatric Research

Volume: 33, P: 313-320
Epstein-Barr Virus-Transformed B-Cell Line (DV-1) Derived from Bone Marrow of a Patient with Severe Combined Immunodeficiency and Immunoblastic Lymphoma

Howard M Rosenblatt
Dorothy E Lewis
William T Shearer
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 331-337
Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models

Obesity and its associated metabolic changes, including hyperinsulinemia and aberrant circadian rhythms, increases the risk for a variety of cancers including postmenopausal breast cancer. Here, the authors show that restricting when mice eat, but not what or how much they eat, delays breast cancer initiation and reduces tumor growth in obese mice in addition to improving insulin sensitivity and restoring circadian rhythms.

Manasi Das
Lesley G. Ellies
Nicholas J. G. Webster
ResearchOpen Access25 Jan 2021
Nature Communications

Volume: 12, P: 1-19
GROWTH HORMONE (hGH) THERAPY AND TUMOR RECURRENCE OF CHILDREN WITH BRAIN NEOPLASMS AND HYPOPITUITARISM

Silva A Arslanian
Dorothy J Becker
Thomas P Foley Jr
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 163
Autoradiographic Localization of CRF₁ and CRF₂ Binding Sites in Adult Rat Brain

Renee J Primus
Eileen Yevich
Dorothy W Gallager
Research01 Nov 1997
Neuropsychopharmacology

Volume: 17, P: 308-316
Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted

Penicillin and other β-lactam drugs form protein adducts that can facilitate allergic and other drug-directed responses. Here, Deimel et al. describe the pharmacokinetic, immunologic and structural determinants of anti-penicillin antibodies.

Lachlan P. Deimel
Lucile Moynié
Quentin J. Sattentau
ResearchOpen Access10 Aug 2024
Nature Communications

Volume: 15, P: 1-12
Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom

Daire Hanna
Sophie Merrick
Melissa Phillips
ResearchOpen Access24 Apr 2024
British Journal of Cancer

Volume: 130, P: 1916-1920
Detrimental effects of adenosine signaling in sickle cell disease

Yujin Zhang et al. discovered that the concentration of adenosine in the blood is increased both in a mouse model of sickle cell disease and in humans with this disease. Adenosine seems to have a pathological role in this disease, as it induced sickling of human erythrocytes through a mechanism involving activation of the A_2B adenosine receptor. Treatment of the mouse model of sickle cell disease with an agent to lower adenosine levels or with an A_2B adenosine receptor antagonist had beneficial effects, pointing to new therapeutic strategies for this disease.

Yujin Zhang
Yingbo Dai
Yang Xia
Research19 Dec 2010
Nature Medicine

Volume: 17, P: 79-86
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes

Longitudinal genomic and transcriptomic profiling of 1,143 patients with multiple myeloma by the Relating Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile study yields an improved copy number and gene expression subtype scheme, most notably a high-risk proliferative subtype associated with complete loss of RB1 or MAX.

Sheri Skerget
Daniel Penaherrera
Jonathan J. Keats
ResearchOpen Access19 Aug 2024
Nature Genetics

Volume: 56, P: 1878-1889
Cytogenetic and molecular study of four couples with multiple trisomy 21 pregnancies

Rowena S James
Katrina Ellis
Patricia A Jacobs
Research29 Jun 1998
European Journal of Human Genetics

Volume: 6, P: 207-212
Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness

Indirect DNA damage to cells cultured below a cellular barrier caused by nanoparticles occurs across barriers containing two or more layers, but not monolayer barriers, suggesting that the thickness of the cell barrier is important in signalling.

A. Sood
S. Salih
C. P. Case
Research06 Nov 2011
Nature Nanotechnology

Volume: 6, P: 824-833
Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment

Nephrotic syndrome is the second most common chronic kidney disease but there are no targeted treatment strategies available. Here the authors identify mutations of six genes codifying for proteins involved in cytoskeleton remodelling and modulation of small GTPases in 17 families with nephrotic syndrome.

Shazia Ashraf
Hiroki Kudo
Friedhelm Hildebrandt
ResearchOpen Access17 May 2018
Nature Communications

Volume: 9, P: 1-14
Congenital hypertrophy of the retinal pigment epithelium and APC mutations in two Chinese families with familial adenomatous polyposis

C P Pang
Joyce W Y Keung
Dennis S C Lam
Research01 Jan 2000
Eye

Volume: 14, P: 18-22
Author Correction: Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes

Sheri Skerget
Daniel Penaherrera
Jonathan J. Keats
Amendments and CorrectionsOpen Access09 Jun 2025
Nature Genetics

Volume: 57, P: 1789
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Better analytical methods are needed to extract biological meaning from genome-wide association studies (GWAS) of psychiatric disorders. Here the authors take GWAS data from over 60,000 subjects, including patients with schizophrenia, bipolar disorder and major depression, and identify common etiological pathways shared amongst them.

Colm O'Dushlaine
Lizzy Rossin
Gerome Breen
Research19 Jan 2015
Nature Neuroscience

Volume: 18, P: 199-209
Leukaemia: a model metastatic disease

Disseminated leukaemia cells share many characteristics with metastasizing solid tumour cells. This Perspective discusses the key molecular processes that facilitate leukaemia metastasis, drawing comparisons with leukocyte trafficking and features of solid tumour invasion. Current and future strategies to target leukaemia metastasis are also discussed.

Andrew E. Whiteley
Trevor T. Price
Dorothy A. Sipkins
Reviews05 May 2021
Nature Reviews Cancer

Volume: 21, P: 461-475
Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene

Paul Blezinger
Jijun Wang
Wang Min
Research01 Apr 1999
Nature Biotechnology

Volume: 17, P: 343-348
Risk factors for trisomy 21: Maternal cigarette smoking and oral contraceptive use in a spopulation-based case-control study

Quanhe Yang
Stephanie L Sherman
Sallie B Freeman
Research01 Mar 1999
Genetics in Medicine

Volume: 1, P: 80-88
1136 SERIAL MATURATION OF AUDITORY BRAINSTEM EVOKED POTENTIALS IN PRE-TERM INFANTS

Allan Krumholz
Philip J Goldstein
Evan Charney
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 553
New pathway to polyketides in plants

Stefan Eckermann
Gudrun Schröder
Joachim Schröder
Research26 Nov 1998
Nature

Volume: 396, P: 387-390
The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus)

Researchers from Hawaii and an international consortium have produced a draft genome assembly for 'SunUp', the first commercial virus-resistant transgenic fruit tree. Comparison of this plant genome to those of Arabidopsis and others sheds light on evolution of characteristics such as biosynthesis, starch deposition, control of photosynthesis and pathways for creating volatile compounds.

Ray Ming
Shaobin Hou
Maqsudul Alam
ResearchOpen Access24 Apr 2008
Nature

Volume: 452, P: 991-996
The complex interplay of modifiable risk factors affecting prostate cancer disparities in African American men

African American men are disproportionately affected by prostate cancer in the USA. In this Review, the authors discuss the complex interplay of modifiable risk factors that might underlie the glaring prostate cancer disparities observed.

Jabril R. Johnson
Nicole Mavingire
Rick A. Kittles
Reviews02 Feb 2024
Nature Reviews Urology

Volume: 21, P: 422-432
Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma

Elena V. Knatko
Maureen Higgins
Albena T. Dinkova-Kostova
ResearchOpen Access24 May 2016
Scientific Reports

Volume: 6, P: 1-7
1022 A LYMPHOBLASTOID B-CELL LINE (LBL) DERIVED FROM A 12-YEAR-OLD BOY WITH SEVERE COMBINED IMMUNODEFICIENCY (SCID)

Howard M Rosenblatt
Jerome Ritz
William T Shearer
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 281
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Naomi Wray and colleagues report an analysis of genome-wide association data sets from the Psychiatric Genomics Consortium for five psychiatric disorders. They find that common variation explains 17–29% of the variance in liability and provide further support for a shared genetic etiology for these related psychiatric disorders.

S Hong Lee
Stephan Ripke
Naomi R Wray
Research11 Aug 2013
Nature Genetics

Volume: 45, P: 984-994
DNA Barcode Authentication of Saw Palmetto Herbal Dietary Supplements

Damon P. Little
Marc L. Jeanson
ResearchOpen Access17 Dec 2013
Scientific Reports

Volume: 3, P: 1-6
Quantity versus quality: Optimal methods for cell-free DNA isolation from plasma of pregnant women

Carolina J Jorgez
Dianne D Dang
Farideh Z Bischoff
Research01 Oct 2006
Genetics in Medicine

Volume: 8, P: 615-619
The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities

A comparison of the frequency of pathogenic mutations in 73 genes in the All of Us cohort highlights the differences in pathogenic variation attributed to ancestry.

Eric Venner
Karynne Patterson
Miriam Vos
ResearchOpen Access19 Feb 2024
Communications Biology

Volume: 7, P: 1-11
HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD

Neeti Agarwal
Dinakar Iyer
Ashok Balasubramanyam
ResearchOpen Access17 Oct 2017
Scientific Reports

Volume: 7, P: 1-15
Support for the Microgenderome: Associations in a Human Clinical Population

Amy Wallis
Henry Butt
Dorothy Bruck
ResearchOpen Access13 Jan 2016
Scientific Reports

Volume: 6, P: 1-9

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