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Advanced filters: Author: Dorsa Moezzi Clear advanced filters

Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia

Oxidized phosphatidylcholines found in MS lesions are not just markers of oxidative stress but are also promoters of demyelination and axon injury. Microglia suppress oxidized-phosphatidylcholine-mediated neurodegeneration by phagocytosis through TREM2.

Yifei Dong
Charlotte D’Mello
V. Wee Yong
Research18 Feb 2021
Nature Neuroscience

Volume: 24, P: 489-503
Expression of antioxidant enzymes in lesions of multiple sclerosis and its models

Dorsa Moezzi
Yifei Dong
V. Wee Yong
ResearchOpen Access26 Jul 2022
Scientific Reports

Volume: 12, P: 1-13

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Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia

Expression of antioxidant enzymes in lesions of multiple sclerosis and its models

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