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Evidence for divergent patterns of local selection driving venom variation in Mojave Rattlesnakes (Crotalus scutulatus)

Jason L. Strickland
Cara F. Smith
Christopher L. Parkinson
ResearchOpen Access04 Dec 2018
Scientific Reports

Volume: 8, P: 1-15
Estimation of genome-wide coupling in rattlesnake hybrids provides insight into the process of speciation and its progress

Genomic coupling theory predicts that speciation progress involves the buildup of genomic associations that manifest in aggregate barriers to gene flow. This study develops approaches to quantify genomic coupling and applies them to a rattlesnake hybrid zone.

Yannick Z. Francioli
Justin M. Bernstein
Todd A. Castoe
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-16
The roles of balancing selection and recombination in the evolution of rattlesnake venom

Analysing whole-genome sequences from 68 rattlesnakes, the authors show a role of long-term balancing selection in maintaining diversity of multiple venom gene families and find reduced selective interference of venom genes with neighbouring loci.

Drew R. Schield
Blair W. Perry
Todd A. Castoe
Research18 Jul 2022
Nature Ecology & Evolution

Volume: 6, P: 1367-1380
Squamate reptiles challenge paradigms of genomic repeat element evolution set by birds and mammals

Large-scale patterns of genomic repeat element evolution have been studied mainly in birds and mammals. Here, the authors analyze the genomes of over 60 squamate reptiles and show high variation in repeat elements compared to mammals and birds, and particularly high microsatellite seeding in snakes.

Giulia I. M. Pasquesi
Richard H. Adams
Todd A. Castoe
ResearchOpen Access17 Jul 2018
Nature Communications

Volume: 9, P: 1-11
Population genomic analyses of schistosome parasites highlight critical challenges facing endgame elimination efforts

Jonathan A. Shortt
Laura E. Timm
David D. Pollock
ResearchOpen Access25 Mar 2021
Scientific Reports

Volume: 11, P: 1-11
Physiological demands and signaling associated with snake venom production and storage illustrated by transcriptional analyses of venom glands

Blair W. Perry
Drew R. Schield
Todd A. Castoe
ResearchOpen Access22 Oct 2020
Scientific Reports

Volume: 10, P: 1-10

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Evidence for divergent patterns of local selection driving venom variation in Mojave Rattlesnakes (Crotalus scutulatus)

Estimation of genome-wide coupling in rattlesnake hybrids provides insight into the process of speciation and its progress

The roles of balancing selection and recombination in the evolution of rattlesnake venom

Squamate reptiles challenge paradigms of genomic repeat element evolution set by birds and mammals

Population genomic analyses of schistosome parasites highlight critical challenges facing endgame elimination efforts

Physiological demands and signaling associated with snake venom production and storage illustrated by transcriptional analyses of venom glands

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