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Showing 1–8 of 8 results
Advanced filters: Author: Dustin Garner Clear advanced filters

  • Electron-microscopy data are used to reconstruct the neurons that make up the anterior visual pathway in the Drosophila brain, providing insight into how visual features are encoded to guide navigation.

    • Dustin Garner
    • Emil Kind
    • Sung Soo Kim
    ResearchOpen Access
    Nature
    Volume: 634, P: 181-190

  • FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to facilitate exploration and browsing.

    • Sven Dorkenwald
    • Arie Matsliah
    • Meet Zandawala
    ResearchOpen Access
    Nature
    Volume: 634, P: 124-138

  • An analysis of the Drosophila connectome yields all cell types intrinsic to the optic lobe, and their rules of connectivity.

    • Arie Matsliah
    • Szi-chieh Yu
    • Gregory S. X. E. Jefferis
    ResearchOpen Access
    Nature
    Volume: 634, P: 166-180

  • Interferon (IFN) is an important component of antiviral immunity, but can also be exploited by bacteria for immune evasion. Here the authors show that Listeria monocytogenes (Lm) induces type I IFN to suppress the degradation of Lm virulence proteins, ActA and LLO, and promote Lm infection in an IFITM3-dependent manner, thereby hinting at a potential target for antimicrobial therapy.

    • Joel M. J. Tan
    • Monica E. Garner
    • John H. Brumell
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • The discovery is reported of a small molecule drug, GS-5734, which has antiviral activity against Ebola virus and other filoviruses, and is capable of providing post-exposure therapeutic protection against lethal disease in 100% of drug-treated nonhuman primates infected with Ebola virus; the drug targets viral RNA polymerase and can distribute to sanctuary sites (such as testes, eyes and brain), suggesting that it may be able to clear persistent virus infection.

    • Travis K. Warren
    • Robert Jordan
    • Sina Bavari
    Research
    Nature
    Volume: 531, P: 381-385