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Advanced filters: Author: Dustin W. Wooten Clear advanced filters

Synthesis and preliminary PET imaging of ¹¹C and ¹⁸F isotopologues of the ROS1/ALK inhibitor lorlatinib

Lorlatinib—a ROS1/ALK inhibitor—is currently undergoing clinical trials for the treatment of non-small cell lung cancers. Here the authors develop synthetic routes to¹¹C- and ¹⁸F-labelled lorlatinib, with subsequent PET imaging showing good blood brain barrier permeability in non-human primates.

Thomas Lee Collier
Marc D. Normandin
Neil Vasdev
ResearchOpen Access08 Jun 2017
Nature Communications

Volume: 8, P: 1-12
Dopaminergic frontostriatal pathways in major depressive disorder and childhood sexual abuse: a multimodal neuroimaging investigation

Lauren R. Borchers
Rotem Dan
Diego A. Pizzagalli
Research09 Sept 2025
Molecular Psychiatry

Volume: 31, P: 343-351
Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson’s disease

Bart de Laat
Jocelyn Hoye
Sule Tinaz
ResearchOpen Access09 Feb 2024
npj Parkinson's Disease

Volume: 10, P: 1-7

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