Endometriosis occurs when estrogen-sensitive endometrial cells that are shed to distal sites manage to attach and survive in a foreign, inflammatory environment. A new study reports a unique interaction between a cleaved form of steroid receptor coactivator 1 (SRC-1) and caspase 8 that blocks apoptosis in endometriotic cells, allowing them to survive (pages 1102–1111).
- Matthew T Dyson
- Serdar E Bulun
