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Cell Death & Disease (3)
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Showing 1–6 of 6 results

Advanced filters: Author: E S J Arnér Clear advanced filters

Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver

NADPH acts as a reducing currency in mammalian cells and is thought to be required to maintain redox homeostasis. Here the authors discover an alternative NADPH-independent pathway, based on the conversion of methionine into cysteine, which is capable of sustaining redox homeostasis in the mouse liver.

Sofi Eriksson
Justin R. Prigge
Edward E. Schmidt
Research20 Mar 2015
Nature Communications

Volume: 6, P: 1-9
Exploiting the 21st amino acid—purifying and labeling proteins by selenolate targeting

Linda Johansson
Chunying Chen
Elias S J Arnér
Research29 Sept 2004
Nature Methods

Volume: 1, P: 61-66
APR-246/PRIMA-1^MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase

X Peng
M-Q-Z Zhang
K G Wiman
ResearchOpen Access24 Oct 2013
Cell Death & Disease

Volume: 4, P: e881
ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis

Y Shi
F Nikulenkov
G Selivanova
ResearchOpen Access10 Jan 2014
Cell Death & Differentiation

Volume: 21, P: 612-623
Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H₂O₂

X Peng
P K Mandal
E S J Arnér
ResearchOpen Access22 May 2014
Cell Death & Disease

Volume: 5, P: e1235
The conserved Trp114 residue of thioredoxin reductase 1 has a redox sensor-like function triggering oligomerization and crosslinking upon oxidative stress related to cell death

J Xu
S E Eriksson
E S J Arnér
ResearchOpen Access22 Jan 2015
Cell Death & Disease

Volume: 6, P: e1616